GO Annotations Graph

• Symbol: Syt6
• Name: synaptotagmin VI
• ID: MGI:1859544

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IBA	J:265628
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IDA	J:235272
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	IBA	J:265628
Molecular Function	GO:0048306	calcium-dependent protein binding	IPI	J:99919
Molecular Function	GO:0048306	calcium-dependent protein binding	IPI	J:99919
Molecular Function	GO:0030276	clathrin binding	ISO	J:164563
Molecular Function	GO:0030276	clathrin binding	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	IPI	J:62060
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0001786	phosphatidylserine binding	IDA	J:232992
Molecular Function	GO:0001786	phosphatidylserine binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:62060
Molecular Function	GO:0005515	protein binding	IPI	J:175346
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:175125
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:175125
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:62060
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:175125
Cellular Component	GO:0019898	extrinsic component of membrane	IDA	J:175125
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:175125
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	IDA	J:175125
Cellular Component	GO:0005886	plasma membrane	IDA	J:175125
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0097060	synaptic membrane	ISO	J:155856
Biological Process	GO:0060478	acrosomal vesicle exocytosis	ISO	J:164563
Biological Process	GO:0007340	acrosome reaction	IDA	J:99919
Biological Process	GO:0017156	calcium-ion regulated exocytosis	IBA	J:265628
Biological Process	GO:0071277	cellular response to calcium ion	IBA	J:265628
Biological Process	GO:0150038	postsynaptic dense core vesicle exocytosis	ISO	J:155856
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IBA	J:265628
Biological Process	GO:0014059	regulation of dopamine secretion	IBA	J:265628