GO Annotations Graph

• Symbol: Foxe3
• Name: forkhead box E3
• ID: MGI:1353569

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISS	J:220565
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:59880
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:76605
Cellular Component	GO:0005634	nucleus	IDA	J:119940
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:59880
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0043010	camera-type eye development	IMP	J:68340
Biological Process	GO:0048468	cell development	IMP	J:101355
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0061073	ciliary body morphogenesis	IMP	J:119940
Biological Process	GO:0061303	cornea development in camera-type eye	IMP	J:119940
Biological Process	GO:0050673	epithelial cell proliferation	IMP	J:101355
Biological Process	GO:0001654	eye development	ISO	J:164563
Biological Process	GO:0001654	eye development	IMP	J:59880
Biological Process	GO:0061072	iris morphogenesis	IMP	J:119940
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:119940
Biological Process	GO:0002088	lens development in camera-type eye	ISO	J:164563
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISS	J:220587
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	IMP	J:63706
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	IMP	J:101355
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	IMP	J:59880
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:101355
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IMP	J:101355
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	IMP	J:101355
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	IMP	J:59880
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	ISS	J:220587
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	ISS	J:220587
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0002930	trabecular meshwork development	IMP	J:119940
Biological Process	GO:0006366	transcription by RNA polymerase II	ISO	J:59880