Tcirg1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Tcirg1
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
MGI:1350931

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051117	ATPase binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:278051
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0005770	late endosome	IDA	J:150327
Cellular Component	GO:0005770	late endosome	IDA	J:83868
Cellular Component	GO:0005764	lysosome	IDA	J:150327
Cellular Component	GO:0005764	lysosome	IDA	J:83868
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	IDA	J:183295
Cellular Component	GO:0045335	phagocytic vesicle	IDA	J:150327
Cellular Component	GO:0030670	phagocytic vesicle membrane	IDA	J:150327
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:61380
Cellular Component	GO:0005886	plasma membrane	IDA	J:83868
Cellular Component	GO:0030667	secretory granule membrane	IDA	J:116082
Cellular Component	GO:0016471	vacuolar proton-transporting V-type ATPase complex	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IMP	J:274229
Biological Process	GO:0006915	apoptotic process	IMP	J:196503
Biological Process	GO:0000045	autophagosome assembly	IMP	J:274229
Biological Process	GO:0006914	autophagy	IMP	J:274229
Biological Process	GO:0030183	B cell differentiation	IMP	J:93047
Biological Process	GO:0030183	B cell differentiation	IMP	J:111910
Biological Process	GO:0030183	B cell differentiation	IMP	J:92730
Biological Process	GO:0045453	bone resorption	IMP	J:274229
Biological Process	GO:0045453	bone resorption	IMP	J:194087
Biological Process	GO:0045453	bone resorption	IMP	J:196503
Biological Process	GO:0045453	bone resorption	IMP	J:180981
Biological Process	GO:0045453	bone resorption	IMP	J:143799
Biological Process	GO:0071345	cellular response to cytokine stimulus	IMP	J:92730
Biological Process	GO:0097188	dentin mineralization	IMP	J:193881
Biological Process	GO:0070166	enamel mineralization	IMP	J:193881
Biological Process	GO:0030010	establishment of cell polarity	IMP	J:274229
Biological Process	GO:0051650	establishment of vesicle localization	IMP	J:278051
Biological Process	GO:0010467	gene expression	IMP	J:274229
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	IMP	J:182505
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:180981
Biological Process	GO:0048872	homeostasis of number of cells	IMP	J:182505
Biological Process	GO:0016064	immunoglobulin mediated immune response	IMP	J:108136
Biological Process	GO:0002377	immunoglobulin production	IMP	J:92730
Biological Process	GO:0006954	inflammatory response	IMP	J:194087
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IMP	J:151255
Biological Process	GO:0051452	intracellular pH reduction	IMP	J:274229
Biological Process	GO:0016236	macroautophagy	IMP	J:199115
Biological Process	GO:0035709	memory T cell activation	IMP	J:108136
Biological Process	GO:0030099	myeloid cell differentiation	IMP	J:93047
Biological Process	GO:0042476	odontogenesis	IMP	J:183295
Biological Process	GO:0021554	optic nerve development	IMP	J:162757
Biological Process	GO:0001503	ossification	IMP	J:180981
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:274229
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:143799
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:196503
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:183295
Biological Process	GO:0030316	osteoclast differentiation	IMP	J:194087
Biological Process	GO:0002158	osteoclast proliferation	IMP	J:180981
Biological Process	GO:0045851	pH reduction	IMP	J:196087
Biological Process	GO:0045851	pH reduction	IMP	J:151255
Biological Process	GO:0090383	phagosome acidification	IMP	J:150327
Biological Process	GO:0007039	protein catabolic process in the vacuole	IMP	J:199115
Biological Process	GO:0033365	protein localization to organelle	IMP	J:278051
Biological Process	GO:0010468	regulation of gene expression	IMP	J:92730
Biological Process	GO:0010468	regulation of gene expression	IMP	J:196087
Biological Process	GO:0010468	regulation of gene expression	IMP	J:196503
Biological Process	GO:0050796	regulation of insulin secretion	IMP	J:116082
Biological Process	GO:0045667	regulation of osteoblast differentiation	IMP	J:182505
Biological Process	GO:0010155	regulation of proton transport	IMP	J:196503
Biological Process	GO:0010272	response to silver ion	IMP	J:92730
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:162757
Biological Process	GO:0031529	ruffle organization	IMP	J:274229
Biological Process	GO:0030217	T cell differentiation	IMP	J:92730
Biological Process	GO:0043029	T cell homeostasis	IMP	J:194087
Biological Process	GO:0035711	T-helper 1 cell activation	IMP	J:93047
Biological Process	GO:0044691	tooth eruption	IMP	J:183295
Biological Process	GO:0032609	type II interferon production	IMP	J:93047
Biological Process	GO:0007035	vacuolar acidification	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23