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GO Annotations Graph
Symbol
Name
ID
Macroh2a1
macroH2A.1 histone
MGI:1349392

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0003682chromatin bindingIDAJ:77519
Molecular FunctionGO:0031490chromatin DNA bindingISOJ:164563
Molecular FunctionGO:0001046core promoter sequence-specific DNA bindingIDAJ:219091
Molecular FunctionGO:0003677DNA bindingIEAJ:60000
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0010385double-stranded methylated DNA bindingISOJ:164563
Molecular FunctionGO:0019899enzyme bindingISOJ:164563
Molecular FunctionGO:0031492nucleosomal DNA bindingIDAJ:219091
Molecular FunctionGO:0031492nucleosomal DNA bindingISOJ:164563
Molecular FunctionGO:0046982protein heterodimerization activityIEAJ:72247
Molecular FunctionGO:0019901protein kinase bindingISOJ:164563
Molecular FunctionGO:0030291protein serine/threonine kinase inhibitor activityISOJ:164563
Molecular FunctionGO:0000182rDNA bindingISOJ:164563
Molecular FunctionGO:0000979RNA polymerase II core promoter sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0000977RNA polymerase II regulatory region sequence-specific DNA bindingISOJ:164563
Molecular FunctionGO:0044212transcription regulatory region DNA bindingISOJ:164563
Cellular ComponentGO:0001740Barr bodyISOJ:89037
Cellular ComponentGO:0001740Barr bodyISOJ:164563
Cellular ComponentGO:0005813centrosomeTASJ:77519
Cellular ComponentGO:0000785chromatinISOJ:155856
Cellular ComponentGO:0005694chromosomeIEAJ:60000
Cellular ComponentGO:0000793condensed chromosomeIDAJ:77519
Cellular ComponentGO:0035098colocalizes_with
ESC/E(Z) complex
ISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0000790nuclear chromatinIBAJ:161428
Cellular ComponentGO:0000790nuclear chromatinISOJ:164563
Cellular ComponentGO:0000228nuclear chromosomeISOJ:164563
Cellular ComponentGO:0000784nuclear chromosome, telomeric regionISOJ:164563
Cellular ComponentGO:0005730nucleolusISOJ:164563
Cellular ComponentGO:0000786nucleosomeISOJ:155856
Cellular ComponentGO:0005634nucleusIDAJ:79872
Cellular ComponentGO:0005634nucleusIDAJ:220900
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005721pericentric heterochromatinISOJ:164563
Biological ProcessGO:0016568chromatin modificationIEAJ:60000
Biological ProcessGO:0006342chromatin silencingIBAJ:161428
Biological ProcessGO:0007549dosage compensationISOJ:89307
Biological ProcessGO:0071169establishment of protein localization to chromatinISOJ:164563
Biological ProcessGO:1902750negative regulation of cell cycle G2/M phase transitionISOJ:164563
Biological ProcessGO:0045814negative regulation of gene expression, epigeneticISOJ:164563
Biological ProcessGO:0061086negative regulation of histone H3-K27 methylationISOJ:164563
Biological ProcessGO:0051572negative regulation of histone H3-K4 methylationISOJ:164563
Biological ProcessGO:0033128negative regulation of histone phosphorylationISOJ:164563
Biological ProcessGO:1904815negative regulation of protein localization to chromosome, telomeric regionISOJ:164563
Biological ProcessGO:0071901negative regulation of protein serine/threonine kinase activityISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:1901837negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoterISOJ:164563
Biological ProcessGO:1901837negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoterIMPJ:207792
Biological ProcessGO:0006334nucleosome assemblyIEAJ:72247
Biological ProcessGO:0045815positive regulation of gene expression, epigeneticISOJ:164563
Biological ProcessGO:0045618positive regulation of keratinocyte differentiationISOJ:164563
Biological ProcessGO:0034184positive regulation of maintenance of mitotic sister chromatid cohesionISOJ:164563
Biological ProcessGO:0040029regulation of gene expression, epigeneticISOJ:164563
Biological ProcessGO:0031060regulation of histone methylationIBAJ:161428
Biological ProcessGO:0019216regulation of lipid metabolic processISOJ:164563
Biological ProcessGO:0019216regulation of lipid metabolic processIDAJ:220900


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory