Foxc1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Foxc1
forkhead box C1
MGI:1347466

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:67859
Molecular Function	GO:0003677	DNA binding	ISO	J:50747
Molecular Function	GO:0008301	DNA binding, bending	ISO	J:164563
Molecular Function	GO:0008301	DNA binding, bending	ISO	J:50747
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:221866
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:140365
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:67859
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:119144
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:221866
Molecular Function	GO:0005515	protein binding	IPI	J:221866
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:221866
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:140365
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0000792	heterochromatin	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:221866
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:71693
Cellular Component	GO:0005634	nucleus	ISO	J:67859
Biological Process	GO:0009653	anatomical structure morphogenesis	IBA	J:265628
Biological Process	GO:0001525	angiogenesis	IEA	J:60000
Biological Process	GO:0003275	apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:0048844	artery morphogenesis	IMP	J:57677
Biological Process	GO:0001568	blood vessel development	IGI	J:119144
Biological Process	GO:0097746	blood vessel diameter maintenance	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:119144
Biological Process	GO:0001974	blood vessel remodeling	IGI	J:71693
Biological Process	GO:0007420	brain development	IMP	J:5191
Biological Process	GO:0007420	brain development	IMP	J:48079
Biological Process	GO:0007420	brain development	IMP	J:5426
Biological Process	GO:0043010	camera-type eye development	IMP	J:56425
Biological Process	GO:0043010	camera-type eye development	IMP	J:61775
Biological Process	GO:0060038	cardiac muscle cell proliferation	IGI	J:119303
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0016477	cell migration	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:1990869	cellular response to chemokine	IMP	J:131323
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0021549	cerebellum development	IMP	J:152710
Biological Process	GO:0070098	chemokine-mediated signaling pathway	IMP	J:131323
Biological Process	GO:0030199	collagen fibril organization	IMP	J:61775
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0035050	embryonic heart tube development	IGI	J:119144
Biological Process	GO:0001958	endochondral ossification	IMP	J:221866
Biological Process	GO:0001654	eye development	IMP	J:48079
Biological Process	GO:0001654	eye development	IMP	J:54407
Biological Process	GO:0001654	eye development	ISO	J:51159
Biological Process	GO:0008354	germ cell migration	IMP	J:105944
Biological Process	GO:0072010	glomerular epithelium development	IMP	J:240396
Biological Process	GO:0030203	glycosaminoglycan metabolic process	IMP	J:5368
Biological Process	GO:0007507	heart development	IGI	J:119303
Biological Process	GO:0007507	heart development	ISO	J:57295
Biological Process	GO:0007507	heart development	IMP	J:57677
Biological Process	GO:0003007	heart morphogenesis	IGI	J:119303
Biological Process	GO:0001701	in utero embryonic development	IMP	J:5431
Biological Process	GO:0001822	kidney development	IMP	J:5191
Biological Process	GO:0001822	kidney development	IMP	J:60834
Biological Process	GO:0032808	lacrimal gland development	IMP	J:107208
Biological Process	GO:0001945	lymph vessel development	IGI	J:119144
Biological Process	GO:0036438	maintenance of lens transparency	IMP	J:181974
Biological Process	GO:0014031	mesenchymal cell development	IDA	J:210256
Biological Process	GO:0048762	mesenchymal cell differentiation	IMP	J:48079
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0016525	negative regulation of angiogenesis	IMP	J:181974
Biological Process	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis	IGI	J:119303
Biological Process	GO:1901491	negative regulation of lymphangiogenesis	IMP	J:181974
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:240396
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0014032	neural crest cell development	IGI	J:119303
Biological Process	GO:0007219	Notch signaling pathway	IGI	J:71693
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	ISO	J:164563
Biological Process	GO:0001503	ossification	IMP	J:85739
Biological Process	GO:0001541	ovarian follicle development	IMP	J:105944
Biological Process	GO:0048341	paraxial mesoderm formation	IMP	J:91443
Biological Process	GO:0048341	paraxial mesoderm formation	IGI	J:71693
Biological Process	GO:1904798	positive regulation of core promoter binding	IMP	J:221866
Biological Process	GO:0043388	positive regulation of DNA binding	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:67853
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:210256
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	IMP	J:210256
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	IMP	J:210256
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:140365
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:221866
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:131323
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:240396
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:119144
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0046620	regulation of organ growth	IGI	J:119303
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0001501	skeletal system development	IMP	J:48079
Biological Process	GO:0001501	skeletal system development	IMP	J:54407
Biological Process	GO:0001501	skeletal system development	IMP	J:5191
Biological Process	GO:0001501	skeletal system development	IMP	J:5426
Biological Process	GO:0001501	skeletal system development	IMP	MGI:MGI:63127
Biological Process	GO:0001756	somitogenesis	IGI	J:71693
Biological Process	GO:0001657	ureteric bud development	IMP	J:60834
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0048010	vascular endothelial growth factor receptor signaling pathway	IGI	J:119144
Biological Process	GO:0038084	vascular endothelial growth factor signaling pathway	IMP	J:181974
Biological Process	GO:0055010	ventricular cardiac muscle tissue morphogenesis	IGI	J:119303

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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