Slc11a2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
MGI:1345279

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0046870	cadmium ion binding	ISO	J:164563
Molecular Function	GO:0046870	cadmium ion binding	ISO	J:155856
Molecular Function	GO:0046870	cadmium ion binding	IBA	J:265628
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015086	cadmium ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0050897	cobalt ion binding	ISO	J:155856
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IDA	J:83962
Molecular Function	GO:0015087	cobalt ion transmembrane transporter activity	IDA	J:84408
Molecular Function	GO:0005507	copper ion binding	ISO	J:155856
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005375	copper ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015093	ferrous iron transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0022890	inorganic cation transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005506	iron ion binding	ISO	J:155856
Molecular Function	GO:0005381	iron ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015094	lead ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0030145	manganese ion binding	ISO	J:155856
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005384	manganese ion transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0046873	metal ion transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0016151	nickel cation binding	ISO	J:155856
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015099	nickel cation transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:1905394	retromer complex binding	ISO	J:164563
Molecular Function	GO:0015295	solute:proton symporter activity	ISO	J:164563
Molecular Function	GO:0046915	transition metal ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015100	vanadium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	ISO	J:155856
Cellular Component	GO:0045177	apical part of cell	ISO	J:164563
Cellular Component	GO:0045177	apical part of cell	IBA	J:265628
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0045178	basal part of cell	ISO	J:164563
Cellular Component	GO:0031526	brush border membrane	IGI	J:151027
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0005769	early endosome	IBA	J:265628
Cellular Component	GO:0005768	endosome	IDA	J:103440
Cellular Component	GO:1903561	extracellular vesicle	IDA	J:236091
Cellular Component	GO:1903561	extracellular vesicle	ISO	J:164563
Cellular Component	GO:1903561	extracellular vesicle	IBA	J:265628
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	ISO	J:155856
Cellular Component	GO:0031902	late endosome membrane	ISO	J:164563
Cellular Component	GO:0031902	late endosome membrane	IBA	J:265628
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:155856
Cellular Component	GO:0005765	lysosomal membrane	ISO	J:164563
Cellular Component	GO:0005765	lysosomal membrane	IBA	J:265628
Cellular Component	GO:0005764	lysosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0070826	paraferritin complex	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:236091
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:103440
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	IBA	J:265628
Cellular Component	GO:0005802	trans-Golgi network	ISO	J:164563
Cellular Component	GO:0005773	vacuole	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0070574	cadmium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0034599	cellular response to oxidative stress	ISO	J:164563
Biological Process	GO:0006824	cobalt ion transport	ISO	J:164563
Biological Process	GO:0006824	cobalt ion transport	IDA	J:84408
Biological Process	GO:0098705	copper ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0006825	copper ion transport	ISO	J:164563
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:146816
Biological Process	GO:0048821	erythrocyte development	IMP	J:98088
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:5555
Biological Process	GO:0006783	heme biosynthetic process	IMP	J:115416
Biological Process	GO:0033212	iron import into cell	ISO	J:164563
Biological Process	GO:0033212	iron import into cell	IBA	J:265628
Biological Process	GO:0033212	iron import into cell	IMP	J:115416
Biological Process	GO:0034755	iron ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	ISO	J:155856
Biological Process	GO:0006826	iron ion transport	ISO	J:164563
Biological Process	GO:0006826	iron ion transport	IMP	J:100202
Biological Process	GO:0006826	iron ion transport	IMP	J:5555
Biological Process	GO:0015692	lead ion transport	ISO	J:164563
Biological Process	GO:0015692	lead ion transport	ISO	J:164563
Biological Process	GO:0007611	learning or memory	IMP	J:146816
Biological Process	GO:0006828	manganese ion transport	ISO	J:164563
Biological Process	GO:0006828	manganese ion transport	ISO	J:164563
Biological Process	GO:0030001	metal ion transport	IEA	J:72247
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	ISO	J:164563
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IBA	J:265628
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:135448
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	IMP	J:5293
Biological Process	GO:0015675	nickel cation transport	ISO	J:164563
Biological Process	GO:0006779	porphyrin-containing compound biosynthetic process	IMP	J:5985
Biological Process	GO:0006778	porphyrin-containing compound metabolic process	IMP	J:31039
Biological Process	GO:0001666	response to hypoxia	IBA	J:265628
Biological Process	GO:0010042	response to manganese ion	ISO	J:155856
Biological Process	GO:0000041	transition metal ion transport	ISO	J:155856
Biological Process	GO:0015676	vanadium ion transport	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23