GO Annotations Graph

• Symbol: Capn10
• Name: calpain 10
• ID: MGI:1344392

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	ISO	J:155856
Molecular Function	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IBA	J:265628
Molecular Function	GO:0008234	cysteine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0008092	cytoskeletal protein binding	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0005743	mitochondrial inner membrane	ISO	J:155856
Cellular Component	GO:0005758	mitochondrial intermembrane space	ISO	J:155856
Cellular Component	GO:0005759	mitochondrial matrix	ISO	J:155856
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0031532	actin cytoskeleton reorganization	IMP	J:133015
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:155856
Biological Process	GO:0007568	aging	ISO	J:155856
Biological Process	GO:0000422	autophagy of mitochondrion	ISO	J:155856
Biological Process	GO:0032869	cellular response to insulin stimulus	IMP	J:133015
Biological Process	GO:0032869	cellular response to insulin stimulus	ISO	J:164563
Biological Process	GO:0007005	mitochondrion organization	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0046326	positive regulation of glucose import	IMP	J:133015
Biological Process	GO:0046326	positive regulation of glucose import	ISO	J:164563
Biological Process	GO:0032024	positive regulation of insulin secretion	ISO	J:164563
Biological Process	GO:0032388	positive regulation of intracellular transport	IMP	J:133015
Biological Process	GO:2000676	positive regulation of type B pancreatic cell apoptotic process	IMP	J:123988
Biological Process	GO:0030163	protein catabolic process	ISO	J:155856
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IBA	J:265628
Biological Process	GO:0031667	response to nutrient levels	ISO	J:155856
Biological Process	GO:0097050	type B pancreatic cell apoptotic process	ISO	J:164563
Biological Process	GO:0097050	type B pancreatic cell apoptotic process	IMP	J:123988