GO Annotations Graph

• Symbol: Dgat1
• Name: diacylglycerol O-acyltransferase 1
• ID: MGI:1333825

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003846	2-acylglycerol O-acyltransferase activity	IDA	J:77354
Molecular Function	GO:0016746	acyltransferase activity	ISO	J:155856
Molecular Function	GO:0019992	diacylglycerol binding	ISO	J:155856
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	ISO	J:164563
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IDA	J:72182
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	ISO	J:155856
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	IBA	J:265628
Molecular Function	GO:0004144	diacylglycerol O-acyltransferase activity	ISO	J:138119
Molecular Function	GO:0005504	fatty acid binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0008374	O-acyltransferase activity	IEA	J:72247
Molecular Function	GO:0050252	retinol O-fatty-acyltransferase activity	IEA	J:72245
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IMP	J:133527
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:61885
Cellular Component	GO:0016020	membrane	IDA	J:72182
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:77354
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Biological Process	GO:0046339	diacylglycerol metabolic process	IDA	J:72182
Biological Process	GO:0046339	diacylglycerol metabolic process	ISO	J:164563
Biological Process	GO:0055089	fatty acid homeostasis	IGI	J:133527
Biological Process	GO:0055089	fatty acid homeostasis	IMP	J:61885
Biological Process	GO:0046486	glycerolipid metabolic process	ISO	J:155856
Biological Process	GO:0030073	insulin secretion	ISO	J:155856
Biological Process	GO:1902224	ketone body metabolic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0019915	lipid storage	IGI	J:180646
Biological Process	GO:0019915	lipid storage	IMP	J:61885
Biological Process	GO:0035336	long-chain fatty-acyl-CoA metabolic process	IDA	J:72182
Biological Process	GO:0006640	monoacylglycerol biosynthetic process	ISO	J:164563
Biological Process	GO:0006640	monoacylglycerol biosynthetic process	IMP	J:242694
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	ISO	J:155856
Biological Process	GO:2000491	positive regulation of hepatic stellate cell activation	ISO	J:155856
Biological Process	GO:0010867	positive regulation of triglyceride biosynthetic process	ISO	J:155856
Biological Process	GO:1903998	regulation of eating behavior	ISO	J:155856
Biological Process	GO:1904729	regulation of intestinal lipid absorption	ISO	J:155856
Biological Process	GO:1901738	regulation of vitamin A metabolic process	ISO	J:155856
Biological Process	GO:0019432	triglyceride biosynthetic process	IDA	J:72182
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:164563
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:155856
Biological Process	GO:0019432	triglyceride biosynthetic process	IMP	J:61885
Biological Process	GO:0019432	triglyceride biosynthetic process	IDA	J:88742
Biological Process	GO:0019432	triglyceride biosynthetic process	IBA	J:265628
Biological Process	GO:0019432	triglyceride biosynthetic process	ISO	J:138119
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	ISO	J:164563