GO Annotations Graph

• Symbol: Ran
• Name: RAN, member RAS oncogene family
• ID: MGI:1333112

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045505	dynein intermediate chain binding	ISO	J:155856
Molecular Function	GO:0003925	G protein activity	ISO	J:164563
Molecular Function	GO:0019003	GDP binding	ISO	J:155856
Molecular Function	GO:0019003	GDP binding	ISO	J:164563
Molecular Function	GO:0005525	GTP binding	ISO	J:155856
Molecular Function	GO:0005525	GTP binding	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	ISO	J:164563
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0061676	importin-alpha family protein binding	ISO	J:155856
Molecular Function	GO:0000287	magnesium ion binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0070883	pre-miRNA binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:222250
Molecular Function	GO:0005515	protein binding	IPI	J:222250
Molecular Function	GO:0005515	protein binding	IPI	J:74290
Molecular Function	GO:0005515	protein binding	IPI	J:74290
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:155856
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005814	centriole	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:137105
Cellular Component	GO:0001673	male germ cell nucleus	ISO	J:155856
Cellular Component	GO:0002177	manchette	ISO	J:155856
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	IDA	J:222250
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005643	nuclear pore	ISO	J:155856
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:222250
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:137105
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0055037	recycling endosome	ISO	J:164563
Cellular Component	GO:0042565	RNA nuclear export complex	ISO	J:164563
Cellular Component	GO:0036126	sperm flagellum	ISO	J:155856
Biological Process	GO:0030036	actin cytoskeleton organization	IMP	J:176957
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0046039	GTP metabolic process	ISO	J:164563
Biological Process	GO:0000070	mitotic sister chromatid segregation	ISO	J:164563
Biological Process	GO:0006913	nucleocytoplasmic transport	IEA	J:72247
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:164563
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0006611	protein export from nucleus	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	ISO	J:164563
Biological Process	GO:0006606	protein import into nucleus	IBA	J:265628
Biological Process	GO:0006606	protein import into nucleus	IDA	J:98705
Biological Process	GO:0006606	protein import into nucleus	IDA	J:74290
Biological Process	GO:0008104	protein localization	IMP	J:176957
Biological Process	GO:1902570	protein localization to nucleolus	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0031503	protein-containing complex localization	IMP	J:176957
Biological Process	GO:0043393	regulation of protein binding	ISO	J:155856
Biological Process	GO:0000055	ribosomal large subunit export from nucleus	ISO	J:164563
Biological Process	GO:0000056	ribosomal small subunit export from nucleus	ISO	J:164563
Biological Process	GO:0000054	ribosomal subunit export from nucleus	IBA	J:265628
Biological Process	GO:0061015	snRNA import into nucleus	ISO	J:164563