GO Annotations Graph

• Symbol: Cldn3
• Name: claudin 3
• ID: MGI:1329044

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:94758
Molecular Function	GO:0005515	protein binding	IPI	J:58914
Molecular Function	GO:0005515	protein binding	IPI	J:94758
Molecular Function	GO:0005515	protein binding	IPI	J:245332
Molecular Function	GO:0005198	structural molecule activity	IEA	J:72247
Cellular Component	GO:0043296	apical junction complex	ISO	J:164563
Cellular Component	GO:0016327	apicolateral plasma membrane	IDA	J:61744
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:164563
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:61744
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:198884
Cellular Component	GO:0005923	bicellular tight junction	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:181271
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:180511
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:180511
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:230002
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:107229
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:181271
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0005911	cell-cell junction	IDA	J:280103
Cellular Component	GO:0005911	cell-cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	IDA	J:181271
Cellular Component	GO:0016020	membrane	NAS	J:61744
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0070830	bicellular tight junction assembly	IBA	J:265628
Biological Process	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	IDA	J:113790
Biological Process	GO:0007155	cell adhesion	IBA	J:265628
Biological Process	GO:0034331	cell junction maintenance	IMP	J:280103
Biological Process	GO:0003382	epithelial cell morphogenesis	IDA	J:198884
Biological Process	GO:0014045	establishment of endothelial blood-brain barrier	IMP	J:280103
Biological Process	GO:0030336	negative regulation of cell migration	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:0061045	negative regulation of wound healing	ISO	J:164563
Biological Process	GO:1903348	positive regulation of bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:1901890	positive regulation of cell junction assembly	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1905050	positive regulation of metallopeptidase activity	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0090303	positive regulation of wound healing	ISO	J:164563
Biological Process	GO:0022604	regulation of cell morphogenesis	ISO	J:164563
Biological Process	GO:0090559	regulation of membrane permeability	ISO	J:164563
Biological Process	GO:0150111	regulation of transepithelial transport	ISO	J:164563