About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Gdf2
growth differentiation factor 2
MGI:1321394

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005125cytokine activityIBAJ:161428
Molecular FunctionGO:0008083growth factor activityIEAJ:60000
Molecular FunctionGO:0008083growth factor activityIEAJ:72247
Molecular FunctionGO:0005515protein bindingIPIJ:164086
Molecular FunctionGO:0005160transforming growth factor beta receptor bindingIBAJ:161428
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005576extracellular regionIEAJ:72247
Cellular ComponentGO:0005615extracellular spaceIBAJ:161428
Biological ProcessGO:0032924activin receptor signaling pathwayISOJ:164563
Biological ProcessGO:0001525angiogenesisISOJ:164563
Biological ProcessGO:0048514blood vessel morphogenesisISOJ:164563
Biological ProcessGO:0030509BMP signaling pathwayIBAJ:161428
Biological ProcessGO:0030509BMP signaling pathwayISOJ:164563
Biological ProcessGO:0048468cell developmentIBAJ:161428
Biological ProcessGO:0006879cellular iron ion homeostasisTASJ:164086
Biological ProcessGO:0071773cellular response to BMP stimulusISOJ:164563
Biological ProcessGO:0006006glucose metabolic processTASJ:164086
Biological ProcessGO:0040007growthIEAJ:72247
Biological ProcessGO:0030308negative regulation of cell growthISOJ:164563
Biological ProcessGO:2000279negative regulation of DNA biosynthetic processISOJ:164563
Biological ProcessGO:0010596negative regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0001937negative regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0030182neuron differentiationTASJ:164086
Biological ProcessGO:0001649osteoblast differentiationIGIJ:146013
Biological ProcessGO:0060389pathway-restricted SMAD protein phosphorylationISOJ:164563
Biological ProcessGO:0001569patterning of blood vesselsISOJ:164563
Biological ProcessGO:0001569patterning of blood vesselsIDAJ:164086
Biological ProcessGO:0045766positive regulation of angiogenesisISOJ:164563
Biological ProcessGO:0045766positive regulation of angiogenesisIDAJ:164086
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayIDAJ:164086
Biological ProcessGO:0061036positive regulation of cartilage developmentIDAJ:219623
Biological ProcessGO:0045603positive regulation of endothelial cell differentiationIDAJ:164086
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationIDAJ:164086
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationISOJ:164563
Biological ProcessGO:0010628positive regulation of gene expressionIDAJ:186473
Biological ProcessGO:0032757positive regulation of interleukin-8 productionISOJ:164563
Biological ProcessGO:0045669positive regulation of osteoblast differentiationIGIJ:91852
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationIBAJ:161428
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIGIJ:146013
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIDAJ:144043
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIMPJ:164086
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedISOJ:164563
Biological ProcessGO:0042981regulation of apoptotic processIBAJ:161428
Biological ProcessGO:0043408regulation of MAPK cascadeIBAJ:161428
Biological ProcessGO:0060395SMAD protein signal transductionIBAJ:161428
Biological ProcessGO:0001570vasculogenesisIDAJ:164086


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/05/2019
MGI 6.14
The Jackson Laboratory