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GO Annotations Graph
Symbol
Name
ID
Slit2
slit guidance ligand 2
MGI:1315205

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005509calcium ion bindingIEAJ:72247
Molecular FunctionGO:0045499chemorepellent activityIMPJ:90079
Molecular FunctionGO:0005095GTPase inhibitor activityISOJ:164563
Molecular FunctionGO:0043395heparan sulfate proteoglycan bindingISOJ:155856
Molecular FunctionGO:0008201heparin bindingIBAJ:161428
Molecular FunctionGO:0008201heparin bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0043237laminin-1 bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:194150
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0043394proteoglycan bindingISOJ:164563
Molecular FunctionGO:0005102receptor bindingTASJ:86040
Molecular FunctionGO:0048495Roundabout bindingIBAJ:161428
Molecular FunctionGO:0048495Roundabout bindingISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0070062extracellular exosomeISOJ:164563
Cellular ComponentGO:0005576extracellular regionIEAJ:60000
Cellular ComponentGO:0005615extracellular spaceIDAJ:86040
Cellular ComponentGO:0005615extracellular spaceISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005578proteinaceous extracellular matrixIBAJ:161428
Biological ProcessGO:0048846axon extension involved in axon guidanceIBAJ:161428
Biological ProcessGO:0048846axon extension involved in axon guidanceISOJ:164563
Biological ProcessGO:0007411axon guidanceIDAJ:87191
Biological ProcessGO:0007411axon guidanceIMPJ:107695
Biological ProcessGO:0007411axon guidanceIGIJ:86465
Biological ProcessGO:0007411axon guidanceIDAJ:86040
Biological ProcessGO:0007411axon guidanceIGIJ:107695
Biological ProcessGO:0007411axon guidanceIGIJ:89780
Biological ProcessGO:0007411axon guidanceISOJ:164563
Biological ProcessGO:0007409axonogenesisIDAJ:109226
Biological ProcessGO:0007409axonogenesisIMPJ:109226
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeISOJ:164563
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0002042cell migration involved in sprouting angiogenesisISOJ:164563
Biological ProcessGO:0071504cellular response to heparinISOJ:164563
Biological ProcessGO:0021952central nervous system projection neuron axonogenesisIBAJ:161428
Biological ProcessGO:0021836chemorepulsion involved in postnatal olfactory bulb interneuron migrationISOJ:164563
Biological ProcessGO:0006935chemotaxisIEAJ:60000
Biological ProcessGO:0021972corticospinal neuron axon guidance through spinal cordISOJ:164563
Biological ProcessGO:0033563dorsal/ventral axon guidanceIGIJ:107695
Biological ProcessGO:0033563dorsal/ventral axon guidanceIMPJ:107695
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:141875
Biological ProcessGO:0050929induction of negative chemotaxisISOJ:164563
Biological ProcessGO:0060763mammary duct terminal end bud growthIMPJ:106011
Biological ProcessGO:0060603mammary gland duct morphogenesisIGIJ:106011
Biological ProcessGO:0060603mammary gland duct morphogenesisIMPJ:106011
Biological ProcessGO:0001656metanephros developmentIMPJ:90324
Biological ProcessGO:0008045motor neuron axon guidanceISOJ:164563
Biological ProcessGO:0007275multicellular organism developmentIEAJ:60000
Biological ProcessGO:0050919negative chemotaxisISOJ:164563
Biological ProcessGO:0050919negative chemotaxisIMPJ:109226
Biological ProcessGO:0050919negative chemotaxisIMPJ:90079
Biological ProcessGO:0030837negative regulation of actin filament polymerizationISOJ:164563
Biological ProcessGO:0030517negative regulation of axon extensionIDAJ:87191
Biological ProcessGO:0030308negative regulation of cell growthISOJ:164563
Biological ProcessGO:0030336negative regulation of cell migrationISOJ:164563
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:141875
Biological ProcessGO:0090288negative regulation of cellular response to growth factor stimulusISOJ:164563
Biological ProcessGO:0070100negative regulation of chemokine-mediated signaling pathwayISOJ:164563
Biological ProcessGO:0010596negative regulation of endothelial cell migrationISOJ:164563
Biological ProcessGO:0010629negative regulation of gene expressionIGIJ:141875
Biological ProcessGO:0034260negative regulation of GTPase activityISOJ:164563
Biological ProcessGO:0050728negative regulation of inflammatory responseISOJ:155856
Biological ProcessGO:0010593negative regulation of lamellipodium assemblyISOJ:164563
Biological ProcessGO:0002689negative regulation of leukocyte chemotaxisISOJ:164563
Biological ProcessGO:0090027negative regulation of monocyte chemotaxisISOJ:155856
Biological ProcessGO:0071676negative regulation of mononuclear cell migrationISOJ:164563
Biological ProcessGO:0090024negative regulation of neutrophil chemotaxisISOJ:164563
Biological ProcessGO:0001933negative regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0090260negative regulation of retinal ganglion cell axon guidanceISOJ:164563
Biological ProcessGO:0051058negative regulation of small GTPase mediated signal transductionISOJ:164563
Biological ProcessGO:0071672negative regulation of smooth muscle cell chemotaxisISOJ:164563
Biological ProcessGO:0014912negative regulation of smooth muscle cell migrationISOJ:164563
Biological ProcessGO:0043116negative regulation of vascular permeabilityISOJ:164563
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0048812neuron projection morphogenesisIMPJ:107695
Biological ProcessGO:0048812neuron projection morphogenesisIGIJ:107695
Biological ProcessGO:0021772olfactory bulb developmentIGIJ:109226
Biological ProcessGO:0043065positive regulation of apoptotic processISOJ:164563
Biological ProcessGO:0031290retinal ganglion cell axon guidanceIMPJ:119315
Biological ProcessGO:0031290retinal ganglion cell axon guidanceIMPJ:111137
Biological ProcessGO:0031290retinal ganglion cell axon guidanceIGIJ:119315
Biological ProcessGO:0031290retinal ganglion cell axon guidanceISOJ:164563
Biological ProcessGO:0031290retinal ganglion cell axon guidanceIGIJ:111137
Biological ProcessGO:0031290retinal ganglion cell axon guidanceIGIJ:73904
Biological ProcessGO:0035385Roundabout signaling pathwayIBAJ:161428
Biological ProcessGO:0035385Roundabout signaling pathwayISOJ:164563
Biological ProcessGO:0016337single organismal cell-cell adhesionIGIJ:106011
Biological ProcessGO:0016337single organismal cell-cell adhesionIMPJ:106011
Biological ProcessGO:0022029telencephalon cell migrationIGIJ:90079
Biological ProcessGO:0001657ureteric bud developmentISOJ:164563


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory