GO Annotations Graph

• Symbol: Slit1
• Name: slit guidance ligand 1
• ID: MGI:1315203

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0043395	heparan sulfate proteoglycan binding	ISO	J:155856
Molecular Function	GO:0008201	heparin binding	IBA	J:265628
Molecular Function	GO:0048495	Roundabout binding	ISO	J:164563
Molecular Function	GO:0048495	Roundabout binding	IBA	J:265628
Molecular Function	GO:0048495	Roundabout binding	IPI	J:56938
Molecular Function	GO:0005102	signaling receptor binding	TAS	J:86040
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:86040
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985822
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-8985829
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9010235
Biological Process	GO:0048846	axon extension involved in axon guidance	ISO	J:164563
Biological Process	GO:0007411	axon guidance	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007411	axon guidance	IGI	J:89780
Biological Process	GO:0007411	axon guidance	IGI	J:77261
Biological Process	GO:0007411	axon guidance	IGI	J:107695
Biological Process	GO:0007411	axon guidance	IDA	J:86040
Biological Process	GO:0007411	axon guidance	IGI	J:89780
Biological Process	GO:0007409	axonogenesis	IDA	J:109226
Biological Process	GO:0007409	axonogenesis	IMP	J:109226
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0033563	dorsal/ventral axon guidance	IGI	J:107695
Biological Process	GO:0008045	motor neuron axon guidance	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050919	negative chemotaxis	ISO	J:164563
Biological Process	GO:0050919	negative chemotaxis	IBA	J:265628
Biological Process	GO:0050919	negative chemotaxis	IMP	J:109226
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0048812	neuron projection morphogenesis	IGI	J:107695
Biological Process	GO:0007097	nuclear migration	IDA	J:77261
Biological Process	GO:0021772	olfactory bulb development	IGI	J:109226
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IGI	J:73904
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IGI	J:111137
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IMP	J:119315
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IGI	J:73904
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IGI	J:119315
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IMP	J:111137
Biological Process	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	IMP	J:90079
Biological Process	GO:0022029	telencephalon cell migration	IGI	J:90079