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GO Annotations Graph
Symbol
Name
ID
Rasgrp1
RAS guanyl releasing protein 1
MGI:1314635

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005509calcium ion bindingISOJ:164563
Molecular FunctionGO:0019992diacylglycerol bindingISOJ:164563
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:72247
Molecular FunctionGO:0005085guanyl-nucleotide exchange factor activityIEAJ:60000
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0031210phosphatidylcholine bindingISOJ:164563
Molecular FunctionGO:0001786phosphatidylserine bindingISOJ:164563
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0005088Ras guanyl-nucleotide exchange factor activityISOJ:164563
Molecular FunctionGO:0008270zinc ion bindingISOJ:164563
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0005783endoplasmic reticulumIEAJ:60000
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0090630activation of GTPase activityISOJ:164563
Biological ProcessGO:0090630activation of GTPase activityIMPJ:65115
Biological ProcessGO:0090630activation of GTPase activityIMPJ:125310
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0001816cytokine productionIMPJ:125310
Biological ProcessGO:0002437inflammatory response to antigenic stimulusIMPJ:125310
Biological ProcessGO:0035556intracellular signal transductionIEAJ:72247
Biological ProcessGO:0043303mast cell degranulationIMPJ:125310
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionISOJ:164563
Biological ProcessGO:0043547positive regulation of GTPase activityISOJ:164563
Biological ProcessGO:1902715positive regulation of interferon-gamma secretionISOJ:164563
Biological ProcessGO:0046330positive regulation of JNK cascadeISOJ:164563
Biological ProcessGO:0043406positive regulation of MAP kinase activityISOJ:164563
Biological ProcessGO:0032816positive regulation of natural killer cell activationIMPJ:179434
Biological ProcessGO:0032825positive regulation of natural killer cell differentiationIMPJ:179434
Biological ProcessGO:0045954positive regulation of natural killer cell mediated cytotoxicityISOJ:164563
Biological ProcessGO:0001934positive regulation of protein phosphorylationISOJ:164563
Biological ProcessGO:0046579positive regulation of Ras protein signal transductionISOJ:164563
Biological ProcessGO:0033089positive regulation of T cell differentiation in thymusIMPJ:65115
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionISOJ:164563
Biological ProcessGO:0051259protein oligomerizationISOJ:164563
Biological ProcessGO:0007265Ras protein signal transductionIEAJ:72247
Biological ProcessGO:0070372regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0043087regulation of GTPase activityIEAJ:72247
Biological ProcessGO:0014066regulation of phosphatidylinositol 3-kinase signalingIMPJ:125310
Biological ProcessGO:0032252secretory granule localizationIMPJ:125310
Biological ProcessGO:0007264small GTPase mediated signal transductionIEAJ:72247
Biological ProcessGO:0047496vesicle transport along microtubuleIMPJ:125310


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory