GO Annotations Graph

• Symbol: Hus1
• Name: HUS1 checkpoint clamp component
• ID: MGI:1277962

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Cellular Component	GO:0030896	checkpoint clamp complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005730	nucleolus	IEA	J:72247
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	IBA	J:265628
Biological Process	GO:0071479	cellular response to ionizing radiation	ISO	J:164563
Biological Process	GO:0000077	DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0000077	DNA damage checkpoint signaling	IMP	J:81636
Biological Process	GO:0006974	DNA damage response	IDA	J:73858
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IDA	J:114813
Biological Process	GO:0000724	double-strand break repair via homologous recombination	IBA	J:265628
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	IMP	J:99339
Biological Process	GO:0044778	meiotic DNA integrity checkpoint signaling	IBA	J:265628
Biological Process	GO:0033314	mitotic DNA replication checkpoint signaling	IBA	J:265628
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	IBA	J:265628
Biological Process	GO:0006289	nucleotide-excision repair	IBA	J:265628
Biological Process	GO:0006468	protein phosphorylation	IDA	J:73858
Biological Process	GO:0006468	protein phosphorylation	IMP	J:81636
Biological Process	GO:0001932	regulation of protein phosphorylation	IMP	J:114798
Biological Process	GO:0009411	response to UV	IDA	J:73858
Biological Process	GO:0009411	response to UV	IMP	J:81636
Biological Process	GO:0000723	telomere maintenance	IBA	J:265628