GO Annotations Graph

• Symbol: Gas8
• Name: growth arrest specific 8
• ID: MGI:1202386

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008017	microtubule binding	IDA	J:233581
Molecular Function	GO:0005515	protein binding	IPI	J:259132
Molecular Function	GO:0005515	protein binding	IPI	J:284740
Molecular Function	GO:0031267	small GTPase binding	IDA	J:136617
Cellular Component	GO:0097729	9+2 motile cilium	IDA	J:234173
Cellular Component	GO:0097729	9+2 motile cilium	EXP	J:253968
Cellular Component	GO:0097729	9+2 motile cilium	EXP	J:253968
Cellular Component	GO:0005930	axoneme	ISO	J:73065
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0036064	ciliary basal body	IDA	J:259132
Cellular Component	GO:0036064	ciliary basal body	IDA	J:233582
Cellular Component	GO:0005929	cilium	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:259132
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:136617
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IBA	J:265628
Cellular Component	GO:0015630	microtubule cytoskeleton	IDA	J:233581
Cellular Component	GO:0031514	motile cilium	ISO	J:164563
Cellular Component	GO:0031514	motile cilium	IDA	J:74672
Cellular Component	GO:0031514	motile cilium	IDA	J:74672
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0036126	sperm flagellum	IDA	J:284740
Cellular Component	GO:0036126	sperm flagellum	IDA	J:74672
Biological Process	GO:0035082	axoneme assembly	ISO	J:164563
Biological Process	GO:0035082	axoneme assembly	IMP	J:234173
Biological Process	GO:0007420	brain development	IMP	J:234173
Biological Process	GO:0007420	brain development	IMP	J:234173
Biological Process	GO:0048870	cell motility	IEA	J:72247
Biological Process	GO:0060294	cilium movement involved in cell motility	ISO	J:164563
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:234173
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:234173
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:234173
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	IMP	J:234173
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:234173
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:234173
Biological Process	GO:0030317	flagellated sperm motility	IEP	J:74672
Biological Process	GO:0030317	flagellated sperm motility	IBA	J:265628
Biological Process	GO:1903566	positive regulation of protein localization to cilium	IDA	J:259132
Biological Process	GO:1903566	positive regulation of protein localization to cilium	ISO	J:164563
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	IMP	J:259132
Biological Process	GO:0008104	protein localization	IDA	J:136617
Biological Process	GO:1904526	regulation of microtubule binding	IDA	J:233581