GO Annotations Graph

• Symbol: Hpn
• Name: hepsin
• ID: MGI:1196620

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	ISO	J:164563
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0070008	serine-type exopeptidase activity	IEA	J:72247
Molecular Function	GO:0008236	serine-type peptidase activity	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IMP	J:123922
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0043025	neuronal cell body	IDA	J:181022
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:84865
Biological Process	GO:0034769	basement membrane disassembly	ISO	J:164563
Biological Process	GO:0042632	cholesterol homeostasis	IMP	J:187708
Biological Process	GO:0090103	cochlea morphogenesis	IMP	J:180548
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:180548
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:181022
Biological Process	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	IMP	J:123922
Biological Process	GO:0060429	epithelium development	IEP	J:180502
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	IMP	J:187708
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	IBA	J:265628
Biological Process	GO:0097195	pilomotor reflex	IMP	J:123922
Biological Process	GO:0043923	positive regulation by host of viral transcription	ISO	J:164563
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:123922
Biological Process	GO:2000347	positive regulation of hepatocyte proliferation	ISO	J:164563
Biological Process	GO:0010756	positive regulation of plasminogen activation	ISO	J:164563
Biological Process	GO:2000611	positive regulation of thyroid hormone generation	IMP	J:123922
Biological Process	GO:0071805	potassium ion transmembrane transport	IMP	J:123922
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0097066	response to thyroid hormone	IMP	J:180548
Biological Process	GO:0007605	sensory perception of sound	IMP	J:187708