GO Annotations Graph

• Symbol: Vps4b
• Name: vacuolar protein sorting 4B
• ID: MGI:1100499

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:72445
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:82243
Molecular Function	GO:0005515	protein binding	IPI	J:90848
Molecular Function	GO:0005515	protein binding	IPI	J:90848
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Cellular Component	GO:1904949	ATPase complex	NAS	J:319973
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:60367
Cellular Component	GO:0005829	cytosol	IDA	J:110348
Cellular Component	GO:0005829	cytosol	IDA	J:90848
Cellular Component	GO:0005768	endosome	ISO	J:72445
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0090543	Flemming body	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030496	midbody	NAS	J:319960
Cellular Component	GO:0005643	nuclear pore	NAS	J:320797
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	NAS	J:319974
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IMP	J:249954
Biological Process	GO:0097352	autophagosome maturation	NAS	J:320408
Biological Process	GO:0006914	autophagy	NAS	J:320141
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:249954
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IMP	J:249954
Biological Process	GO:0030301	cholesterol transport	IMP	J:60367
Biological Process	GO:0016197	endosomal transport	IBA	J:265628
Biological Process	GO:0016197	endosomal transport	ISO	J:72445
Biological Process	GO:0007032	endosome organization	IMP	J:60367
Biological Process	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:1904903	ESCRT III complex disassembly	ISO	J:164563
Biological Process	GO:0060856	establishment of blood-brain barrier	IMP	J:249954
Biological Process	GO:0061738	late endosomal microautophagy	IMP	J:227378
Biological Process	GO:0061764	late endosome to lysosome transport via multivesicular body sorting pathway	NAS	J:320408
Biological Process	GO:0090148	membrane fission	NAS	J:319974
Biological Process	GO:0061952	midbody abscission	NAS	J:320142
Biological Process	GO:0061952	midbody abscission	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0036258	multivesicular body assembly	NAS	J:320797
Biological Process	GO:0036258	multivesicular body assembly	IMP	J:227378
Biological Process	GO:0071985	multivesicular body sorting pathway	NAS	J:320797
Biological Process	GO:0060548	negative regulation of cell death	NAS	J:320141
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:1903542	negative regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0031468	nuclear membrane reassembly	NAS	J:319959
Biological Process	GO:0006997	nucleus organization	NAS	J:320142
Biological Process	GO:0006997	nucleus organization	ISO	J:164563
Biological Process	GO:0001778	plasma membrane repair	NAS	J:319966
Biological Process	GO:1903724	positive regulation of centriole elongation	ISO	J:164563
Biological Process	GO:1903543	positive regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	IDA	J:20181
Biological Process	GO:0051261	protein depolymerization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0010824	regulation of centrosome duplication	ISO	J:164563
Biological Process	GO:1901673	regulation of mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0033993	response to lipid	ISO	J:164563
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0007034	vacuolar transport	IMP	J:249954
Biological Process	GO:0007033	vacuole organization	IBA	J:265628
Biological Process	GO:0046761	viral budding from plasma membrane	ISO	J:164563
Biological Process	GO:0046761	viral budding from plasma membrane	IMP	J:219096
Biological Process	GO:0039702	viral budding via host ESCRT complex	ISO	J:164563