GO Annotations Graph

• Symbol: Per1
• Name: period circadian clock 1
• ID: MGI:1098283

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:209614
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:205048
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	IPI	J:87576
Molecular Function	GO:0005515	protein binding	IPI	J:51392
Molecular Function	GO:0005515	protein binding	IPI	J:170592
Molecular Function	GO:0005515	protein binding	IPI	J:87576
Molecular Function	GO:0005515	protein binding	IPI	J:205048
Molecular Function	GO:0005515	protein binding	IPI	J:189236
Molecular Function	GO:0005515	protein binding	IPI	J:160776
Molecular Function	GO:0005515	protein binding	IPI	J:173532
Molecular Function	GO:0005515	protein binding	IPI	J:215857
Molecular Function	GO:0005515	protein binding	IPI	J:196684
Molecular Function	GO:0005515	protein binding	IPI	J:209570
Molecular Function	GO:0005515	protein binding	IPI	J:57184
Molecular Function	GO:0005515	protein binding	IPI	J:116444
Molecular Function	GO:0005515	protein binding	IPI	J:150148
Molecular Function	GO:0005515	protein binding	IPI	J:200473
Molecular Function	GO:0005515	protein binding	IPI	J:51391
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:210023
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IBA	J:265628
Molecular Function	GO:0001222	transcription corepressor binding	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1856952
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-508627
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-508749
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-517928
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-549491
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-549498
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-508741
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-549498
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:205048
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:73173
Biological Process	GO:0006338	chromatin remodeling	IMP	J:173532
Biological Process	GO:0032922	circadian regulation of gene expression	ISO	J:164563
Biological Process	GO:0032922	circadian regulation of gene expression	IDA	J:156994
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:98340
Biological Process	GO:0032922	circadian regulation of gene expression	IBA	J:265628
Biological Process	GO:0097167	circadian regulation of translation	IMP	J:69626
Biological Process	GO:0007623	circadian rhythm	IEP	J:162974
Biological Process	GO:0007623	circadian rhythm	IEP	J:207820
Biological Process	GO:0007623	circadian rhythm	IEP	J:192252
Biological Process	GO:0007623	circadian rhythm	IEP	J:156337
Biological Process	GO:0007623	circadian rhythm	IEP	J:199564
Biological Process	GO:0007623	circadian rhythm	IEP	J:197826
Biological Process	GO:0007623	circadian rhythm	ISO	J:155856
Biological Process	GO:0007623	circadian rhythm	TAS	J:76640
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	IMP	J:98340
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:135812
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:79730
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:51392
Biological Process	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	IMP	J:209461
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	ISO	J:155856
Biological Process	GO:0046329	negative regulation of JNK cascade	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:178280
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:209614
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:79730
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:52070
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:209614
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IMP	J:98340
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:69626
Biological Process	GO:1900015	regulation of cytokine production involved in inflammatory response	ISO	J:155856
Biological Process	GO:0042634	regulation of hair cycle	ISO	J:164563
Biological Process	GO:1900744	regulation of p38MAPK cascade	ISO	J:155856
Biological Process	GO:0002028	regulation of sodium ion transport	IMP	J:209614
Biological Process	GO:0051591	response to cAMP	IDA	J:197826
Biological Process	GO:0048511	rhythmic process	IEA	J:60000