GO Annotations Graph

• Symbol: Snai2
• Name: snail family zinc finger 2
• ID: MGI:1096393

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:130039
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	J:131871
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IGI	J:115191
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:139512
Molecular Function	GO:0070888	E-box binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:183217
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:155937
Cellular Component	GO:0005737	cytoplasm	IDA	J:155937
Cellular Component	GO:0005737	cytoplasm	IDA	J:155937
Cellular Component	GO:0005737	cytoplasm	IDA	J:155937
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:128085
Cellular Component	GO:0005634	nucleus	IDA	J:155937
Cellular Component	GO:0005634	nucleus	IDA	J:155937
Cellular Component	GO:0005634	nucleus	IDA	J:84568
Cellular Component	GO:0005634	nucleus	IDA	J:155937
Cellular Component	GO:0005634	nucleus	IDA	J:155937
Biological Process	GO:0060536	cartilage morphogenesis	IGI	J:121243
Biological Process	GO:0003273	cell migration involved in endocardial cushion formation	IMP	J:139512
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0071479	cellular response to ionizing radiation	IGI	J:115191
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	TAS	J:139512
Biological Process	GO:0006325	chromatin organization	IMP	J:130039
Biological Process	GO:0035921	desmosome disassembly	IMP	J:41071
Biological Process	GO:0035921	desmosome disassembly	ISO	J:164563
Biological Process	GO:0043542	endothelial cell migration	IMP	J:139512
Biological Process	GO:0010631	epithelial cell migration	IGI	J:121243
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:41071
Biological Process	GO:0001837	epithelial to mesenchymal transition	ISO	J:164563
Biological Process	GO:0001837	epithelial to mesenchymal transition	IMP	J:126938
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	IMP	J:139512
Biological Process	GO:0060429	epithelium development	IMP	J:175151
Biological Process	GO:0071425	hematopoietic stem cell proliferation	IMP	J:157771
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0033028	myeloid cell apoptotic process	IGI	J:115191
Biological Process	GO:0033028	myeloid cell apoptotic process	IGI	J:115191
Biological Process	GO:2000811	negative regulation of anoikis	ISO	J:164563
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	IMP	J:139512
Biological Process	GO:0033629	negative regulation of cell adhesion mediated by integrin	ISO	J:164563
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	ISO	J:164563
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	ISO	J:164563
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IDA	J:175126
Biological Process	GO:1902034	negative regulation of hematopoietic stem cell proliferation	IMP	J:157771
Biological Process	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	ISO	J:164563
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	IGI	J:115191
Biological Process	GO:0033033	negative regulation of myeloid cell apoptotic process	IGI	J:115191
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:131871
Biological Process	GO:0010957	negative regulation of vitamin D biosynthetic process	ISO	J:164563
Biological Process	GO:0070563	negative regulation of vitamin D receptor signaling pathway	ISO	J:164563
Biological Process	GO:0014032	neural crest cell development	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:164563
Biological Process	GO:0043473	pigmentation	IMP	J:80529
Biological Process	GO:0043473	pigmentation	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:2001028	positive regulation of endothelial cell chemotaxis	IC	J:139512
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IMP	J:130039
Biological Process	GO:0045600	positive regulation of fat cell differentiation	IGI	J:130039
Biological Process	GO:0042981	regulation of apoptotic process	IC	J:84568
Biological Process	GO:0042981	regulation of apoptotic process	IC	J:84568
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:0060693	regulation of branching involved in salivary gland morphogenesis	IMP	J:162851
Biological Process	GO:0032642	regulation of chemokine production	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0045667	regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0009314	response to radiation	IDA	J:84568
Biological Process	GO:0009314	response to radiation	IMP	J:84568
Biological Process	GO:0060021	roof of mouth development	IGI	J:121243
Biological Process	GO:0060021	roof of mouth development	IMP	J:121243
Biological Process	GO:0007605	sensory perception of sound	IMP	J:80529
Biological Process	GO:0007605	sensory perception of sound	ISO	J:164563
Biological Process	GO:0006929	substrate-dependent cell migration	IMP	J:139512
Biological Process	GO:0050872	white fat cell differentiation	IGI	J:130039
Biological Process	GO:0050872	white fat cell differentiation	IMP	J:130039
Biological Process	GO:0050872	white fat cell differentiation	IMP	J:130039
Biological Process	GO:0044319	wound healing, spreading of cells	TAS	J:139512