About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
MGI:109482

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005262calcium channel activityIEAJ:60000
Molecular FunctionGO:0005516calmodulin bindingISOJ:155856
Molecular FunctionGO:0003677DNA bindingIEAJ:72247
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIGIJ:75166
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:63634
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:76459
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:96814
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:72853
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:76879
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:112100
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:82722
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:107960
Molecular FunctionGO:0008331high voltage-gated calcium channel activityIMPJ:109231
Molecular FunctionGO:0008331high voltage-gated calcium channel activityISOJ:155856
Molecular FunctionGO:0005216ion channel activityIEAJ:72247
Molecular FunctionGO:0046872metal ion bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:28892
Molecular FunctionGO:0005515protein bindingIPIJ:57712
Molecular FunctionGO:0019905syntaxin bindingISOJ:164563
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:106959
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:59076
Molecular FunctionGO:0005245voltage-gated calcium channel activityISOJ:155856
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:89452
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:47984
Molecular FunctionGO:0005245voltage-gated calcium channel activityIDAJ:31925
Molecular FunctionGO:0005245voltage-gated calcium channel activityISOJ:164563
Molecular FunctionGO:0005245voltage-gated calcium channel activityIMPJ:51647
Molecular FunctionGO:0005244voltage-gated ion channel activityIEAJ:60000
Cellular ComponentGO:0042995cell projectionISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0030425dendriteIDAJ:92975
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016020membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0043025neuronal cell bodyIDAJ:92975
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0043204perikaryonISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043234protein complexISOJ:155856
Cellular ComponentGO:0005891voltage-gated calcium channel complexISOJ:155856
Cellular ComponentGO:0005891voltage-gated calcium channel complexIDAJ:57712
Biological ProcessGO:0007628adult walking behaviorIMPJ:59076
Biological ProcessGO:0007628adult walking behaviorIMPJ:76459
Biological ProcessGO:0007628adult walking behaviorIMPJ:71860
Biological ProcessGO:0007628adult walking behaviorIMPJ:262
Biological ProcessGO:0007628adult walking behaviorIGIJ:36184
Biological ProcessGO:0007628adult walking behaviorIMPJ:113141
Biological ProcessGO:0007628adult walking behaviorIMPMGI:63040
Biological ProcessGO:0007628adult walking behaviorIGIJ:52508
Biological ProcessGO:0007628adult walking behaviorIMPJ:5240
Biological ProcessGO:0007628adult walking behaviorIMPJ:12735
Biological ProcessGO:0007628adult walking behaviorIMPJ:107960
Biological ProcessGO:0007628adult walking behaviorIMPJ:36184
Biological ProcessGO:0048266behavioral response to painIMPJ:113141
Biological ProcessGO:0070509calcium ion importISOJ:155856
Biological ProcessGO:0017156calcium ion regulated exocytosisIMPJ:76879
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:72247
Biological ProcessGO:0070588calcium ion transmembrane transportIEAJ:60000
Biological ProcessGO:0006816calcium ion transportIMPJ:47984
Biological ProcessGO:0006816calcium ion transportIMPJ:89452
Biological ProcessGO:0006816calcium ion transportIMPJ:51647
Biological ProcessGO:0006816calcium ion transportISOJ:155856
Biological ProcessGO:0048791calcium ion-regulated exocytosis of neurotransmitterIMPJ:60492
Biological ProcessGO:0008219cell deathISOJ:164563
Biological ProcessGO:0016049cell growthIMPJ:14500
Biological ProcessGO:0030644cellular chloride ion homeostasisIMPJ:32181
Biological ProcessGO:0030644cellular chloride ion homeostasisIMPJ:103988
Biological ProcessGO:0021953central nervous system neuron differentiationIMPJ:6615
Biological ProcessGO:0021679cerebellar molecular layer developmentIMPJ:22482
Biological ProcessGO:0021702cerebellar Purkinje cell differentiationIMPJ:14500
Biological ProcessGO:0021702cerebellar Purkinje cell differentiationIMPJ:58539
Biological ProcessGO:0021702cerebellar Purkinje cell differentiationIMPJ:20921
Biological ProcessGO:0021680cerebellar Purkinje cell layer developmentIMPJ:14500
Biological ProcessGO:0021590cerebellum maturationIMPJ:76459
Biological ProcessGO:0048813dendrite morphogenesisIMPJ:55268
Biological ProcessGO:0048813dendrite morphogenesisIMPJ:90116
Biological ProcessGO:0048813dendrite morphogenesisIMPJ:71860
Biological ProcessGO:0014051gamma-aminobutyric acid secretionIMPJ:60492
Biological ProcessGO:0007214gamma-aminobutyric acid signaling pathwayIMPJ:32181
Biological ProcessGO:0006006glucose metabolic processIMPJ:40690
Biological ProcessGO:0042445hormone metabolic processIMPJ:40690
Biological ProcessGO:0042445hormone metabolic processIMPJ:15508
Biological ProcessGO:0006811ion transportIEAJ:72247
Biological ProcessGO:0006811ion transportIEAJ:60000
Biological ProcessGO:0051899membrane depolarizationIMPJ:18102
Biological ProcessGO:0051899membrane depolarizationIMPJ:72853
Biological ProcessGO:0051899membrane depolarizationIMPJ:63634
Biological ProcessGO:0086010membrane depolarization during action potentialIBAJ:161428
Biological ProcessGO:0050883musculoskeletal movement, spinal reflex actionIMPJ:72853
Biological ProcessGO:0032353negative regulation of hormone biosynthetic processIMPJ:110939
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIMPJ:36596
Biological ProcessGO:0043524negative regulation of neuron apoptotic processIMPJ:5240
Biological ProcessGO:0050877neurological system processIMPJ:3611
Biological ProcessGO:0050877neurological system processIMPJ:7519
Biological ProcessGO:0050905neuromuscular processIGIJ:58539
Biological ProcessGO:0050905neuromuscular processIMPJ:76459
Biological ProcessGO:0050885neuromuscular process controlling balanceIMPJ:12735
Biological ProcessGO:0007274neuromuscular synaptic transmissionIMPJ:102080
Biological ProcessGO:0007270neuron-neuron synaptic transmissionIMPJ:106709
Biological ProcessGO:0042133neurotransmitter metabolic processIMPJ:14712
Biological ProcessGO:0042133neurotransmitter metabolic processIMPJ:6553
Biological ProcessGO:0042133neurotransmitter metabolic processIMPJ:633
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationIDAJ:31925
Biological ProcessGO:0007204positive regulation of cytosolic calcium ion concentrationISOJ:164563
Biological ProcessGO:0043113receptor clusteringIMPJ:82722
Biological ProcessGO:0014056regulation of acetylcholine secretion, neurotransmissionIMPJ:82722
Biological ProcessGO:0014056regulation of acetylcholine secretion, neurotransmissionIMPJ:102080
Biological ProcessGO:0050770regulation of axonogenesisIMPJ:6154
Biological ProcessGO:0017158regulation of calcium ion-dependent exocytosisIDAJ:31925
Biological ProcessGO:0034765regulation of ion transmembrane transportIEAJ:60000
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:1180
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:106959
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:47984
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:51647
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:3627
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:107960
Biological ProcessGO:0042391regulation of membrane potentialIMPJ:60492
Biological ProcessGO:0048265response to painIMPJ:72853
Biological ProcessGO:0060024rhythmic synaptic transmissionIMPJ:107094
Biological ProcessGO:0019233sensory perception of painISOJ:155856
Biological ProcessGO:0021522spinal cord motor neuron differentiationIMPJ:135940
Biological ProcessGO:0000096sulfur amino acid metabolic processIMPJ:12200
Biological ProcessGO:0007416synapse assemblyIMPJ:90116
Biological ProcessGO:0007416synapse assemblyIMPJ:55268
Biological ProcessGO:0007268synaptic transmissionIMPJ:109231
Biological ProcessGO:0007268synaptic transmissionIMPJ:96814
Biological ProcessGO:0007268synaptic transmissionISOJ:155856
Biological ProcessGO:0007268synaptic transmissionIMPJ:59076
Biological ProcessGO:0035249synaptic transmission, glutamatergicIMPJ:90116
Biological ProcessGO:0035249synaptic transmission, glutamatergicIMPJ:56225
Biological ProcessGO:0042403thyroid hormone metabolic processIMPMGI:85368
Biological ProcessGO:0055085transmembrane transportIEAJ:72247
Biological ProcessGO:0019226transmission of nerve impulseIMPJ:1180
Biological ProcessGO:0019226transmission of nerve impulseIMPJ:3190
Biological ProcessGO:0019226transmission of nerve impulseIMPJ:3627
Biological ProcessGO:0006810transportIEAJ:60000
Biological ProcessGO:0021750vestibular nucleus developmentIMPJ:30260


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
11/22/2022
MGI 6.22
The Jackson Laboratory