Atf2 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Atf2
activating transcription factor 2
MGI:109349

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0035497	cAMP response element binding	ISO	J:164563
Molecular Function	GO:0035497	cAMP response element binding	ISO	J:155856
Molecular Function	GO:0035497	cAMP response element binding	IBA	J:265628
Molecular Function	GO:0035497	cAMP response element binding	IDA	J:67261
Molecular Function	GO:0008140	cAMP response element binding protein binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:125640
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:79339
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ISO	J:164563
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:156376
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:35340
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0044013	histone H2B acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0010485	histone H4 acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0043522	leucine zipper domain binding	IPI	J:67261
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:141299
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:121664
Molecular Function	GO:0005515	protein binding	IPI	J:115171
Molecular Function	GO:0005515	protein binding	IPI	J:47012
Molecular Function	GO:0005515	protein binding	IPI	J:292035
Molecular Function	GO:0005515	protein binding	IPI	J:49834
Molecular Function	GO:0005515	protein binding	IPI	J:50355
Molecular Function	GO:0005515	protein binding	IPI	J:67261
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:67261
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:49834
Molecular Function	GO:0042803	protein homodimerization activity	IPI	J:67261
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:105537
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IMP	J:240286
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0016602	CCAAT-binding factor complex	ISO	J:36128
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:1902562	H4 histone acetyltransferase complex	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:90586
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:156376
Cellular Component	GO:0005634	nucleus	ISO	J:35340
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	IMP	J:240286
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Biological Process	GO:0021742	abducens nucleus development	IMP	J:172398
Biological Process	GO:0060612	adipose tissue development	IGI	J:156376
Biological Process	GO:0097186	amelogenesis	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IMP	J:118986
Biological Process	GO:1902742	apoptotic process involved in development	IMP	J:172398
Biological Process	GO:0030509	BMP signaling pathway	IMP	J:156376
Biological Process	GO:0003360	brainstem development	IMP	J:172398
Biological Process	GO:0044255	cellular lipid metabolic process	IMP	J:172398
Biological Process	GO:0072740	cellular response to anisomycin	IMP	J:118986
Biological Process	GO:0072740	cellular response to anisomycin	IDA	J:150642
Biological Process	GO:0072740	cellular response to anisomycin	IMP	J:150642
Biological Process	GO:1990253	cellular response to leucine starvation	IMP	J:172398
Biological Process	GO:0034599	cellular response to oxidative stress	IMP	J:123909
Biological Process	GO:0098586	cellular response to virus	IDA	J:141299
Biological Process	GO:0060245	detection of cell density	IMP	J:118986
Biological Process	GO:0006974	DNA damage response	IMP	J:240286
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0021754	facial nucleus development	IMP	J:172398
Biological Process	GO:0010467	gene expression	IMP	J:172398
Biological Process	GO:0010467	gene expression	IMP	J:139039
Biological Process	GO:0010467	gene expression	IMP	J:150642
Biological Process	GO:0010467	gene expression	IDA	J:105537
Biological Process	GO:0010467	gene expression	IMP	J:139039
Biological Process	GO:0010467	gene expression	IMP	J:156376
Biological Process	GO:0010467	gene expression	IMP	J:139039
Biological Process	GO:0010467	gene expression	IMP	J:167512
Biological Process	GO:0003418	growth plate cartilage chondrocyte differentiation	IMP	J:139039
Biological Process	GO:0003419	growth plate cartilage chondrocyte proliferation	IMP	J:139039
Biological Process	GO:0007507	heart development	IGI	J:123909
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IGI	J:123909
Biological Process	GO:0097284	hepatocyte apoptotic process	IGI	J:123909
Biological Process	GO:0021743	hypoglossal nucleus development	IMP	J:172398
Biological Process	GO:0001701	in utero embryonic development	IGI	J:123909
Biological Process	GO:0001701	in utero embryonic development	IMP	J:123909
Biological Process	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia	IMP	J:118986
Biological Process	GO:0007254	JNK cascade	IMP	J:172398
Biological Process	GO:0007254	JNK cascade	IMP	J:141299
Biological Process	GO:0001889	liver development	IGI	J:123909
Biological Process	GO:0000165	MAPK cascade	IMP	J:141299
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	ISO	J:164563
Biological Process	GO:0097049	motor neuron apoptotic process	IMP	J:172398
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IMP	J:139039
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:164563
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0060052	neurofilament cytoskeleton organization	IMP	J:172398
Biological Process	GO:0001865	NK T cell differentiation	IMP	J:127589
Biological Process	GO:0003151	outflow tract morphogenesis	IMP	J:125640
Biological Process	GO:0038066	p38MAPK cascade	IMP	J:156376
Biological Process	GO:0038066	p38MAPK cascade	IMP	J:172398
Biological Process	GO:0038066	p38MAPK cascade	IGI	J:123909
Biological Process	GO:0110024	positive regulation of cardiac muscle myoblast proliferation	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	ISO	J:164563
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	ISO	J:155856
Biological Process	GO:0001934	positive regulation of protein phosphorylation	IMP	J:105537
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:121664
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:105537
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:121664
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:50355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:50355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:141299
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:156376
Biological Process	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	IDA	J:150642
Biological Process	GO:0032915	positive regulation of transforming growth factor beta2 production	IMP	J:125640
Biological Process	GO:0006606	protein import into nucleus	IDA	J:292035
Biological Process	GO:1901976	regulation of cell cycle checkpoint	IMP	J:139039
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IDA	J:67261
Biological Process	GO:0014070	response to organic cyclic compound	IMP	J:131564
Biological Process	GO:0006970	response to osmotic stress	ISO	J:164563
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	ISO	J:164563
Biological Process	GO:0007033	vacuole organization	IMP	J:172398
Biological Process	GO:0050872	white fat cell differentiation	IGI	J:156376
Biological Process	GO:0050872	white fat cell differentiation	IMP	J:156376
Biological Process	GO:0050872	white fat cell differentiation	IGI	J:156376

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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