GO Annotations Graph

• Symbol: Npas2
• Name: neuronal PAS domain protein 2
• ID: MGI:109232

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:209471
Molecular Function	GO:0003677	DNA binding	ISO	J:73065
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IEA	J:72247
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0051879	Hsp90 protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:207820
Molecular Function	GO:0046983	protein dimerization activity	IEA	J:72247
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:1990513	CLOCK-BMAL transcription complex	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IEA	J:72247
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-508619
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-508656
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-549451
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5663263
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-508656
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-508741
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663114
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663129
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663146
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663147
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663158
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663161
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663172
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663185
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5663189
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5669295
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-8878686
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:73065
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:135812
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:202325
Biological Process	GO:0032922	circadian regulation of gene expression	IMP	J:271703
Biological Process	GO:0032922	circadian regulation of gene expression	IBA	J:265628
Biological Process	GO:0007623	circadian rhythm	IEP	J:207820
Biological Process	GO:0042745	circadian sleep/wake cycle	IMP	J:84471
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0045475	locomotor rhythm	IMP	J:84471
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:2000987	positive regulation of behavioral fear response	IMP	J:271703
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:274080
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:202325
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:135812
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0042752	regulation of circadian rhythm	IMP	J:202325
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0051775	response to redox state	IDA	J:209471
Biological Process	GO:0051775	response to redox state	ISO	J:164563
Biological Process	GO:0009410	response to xenobiotic stimulus	IMP	J:271703
Biological Process	GO:0048511	rhythmic process	IEA	J:60000