GO Annotations Graph

• Symbol: Sirpa
• Name: signal-regulatory protein alpha
• ID: MGI:108563

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Wed Mar 2 12:11:24 2016.

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:84084
Molecular Function	GO:0005515	protein binding	IPI	J:86931
Molecular Function	GO:0005515	protein binding	IPI	J:75835
Molecular Function	GO:0005515	protein binding	IPI	J:86609
Molecular Function	GO:0045309	protein phosphorylated amino acid binding	IPI	J:80118
Molecular Function	GO:0017124	SH3 domain binding	IEA	J:60000
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0016021	integral component of membrane	IEA	J:60000
Cellular Component	GO:0005887	integral component of plasma membrane	IDA	J:86609
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0007015	actin filament organization	IMP	J:79824
Biological Process	GO:0016477	cell migration	ISO	J:155856
Biological Process	GO:0007160	cell-matrix adhesion	IMP	J:79824
Biological Process	GO:0007010	cytoskeleton organization	IMP	J:79824
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	IMP	J:202604
Biological Process	GO:0006928	movement of cell or subcellular component	IMP	J:79824
Biological Process	GO:0006911	phagocytosis, engulfment	IDA	J:86609
Biological Process	GO:0006910	phagocytosis, recognition	IDA	J:86609
Biological Process	GO:0050766	positive regulation of phagocytosis	IDA	J:86609

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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