Fzd4 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Fzd4
frizzled class receptor 4
MGI:108520

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001540	amyloid-beta binding	ISO	J:164563
Molecular Function	GO:0019955	cytokine binding	IPI	J:107732
Molecular Function	GO:0019955	cytokine binding	ISO	J:164563
Molecular Function	GO:0004896	cytokine receptor activity	ISO	J:164563
Molecular Function	GO:0004930	G protein-coupled receptor activity	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:200510
Molecular Function	GO:0005515	protein binding	IPI	J:255327
Molecular Function	GO:0005515	protein binding	IPI	J:130925
Molecular Function	GO:0005515	protein binding	IPI	J:175224
Molecular Function	GO:0005515	protein binding	IPI	J:163736
Molecular Function	GO:0005515	protein binding	IPI	J:99178
Molecular Function	GO:0005515	protein binding	IPI	J:175224
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:155856
Molecular Function	GO:0038023	signaling receptor activity	IGI	J:255327
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IEA	J:72247
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0042813	Wnt receptor activity	ISO	J:164563
Molecular Function	GO:0042813	Wnt receptor activity	IBA	J:265628
Molecular Function	GO:0042813	Wnt receptor activity	IPI	J:101493
Molecular Function	GO:0017147	Wnt-protein binding	IPI	J:163140
Molecular Function	GO:0017147	Wnt-protein binding	ISO	J:155856
Molecular Function	GO:0017147	Wnt-protein binding	IBA	J:265628
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0005911	cell-cell junction	IDA	J:163736
Cellular Component	GO:0030425	dendrite	IMP	J:255327
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263445
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:107732
Cellular Component	GO:0005886	plasma membrane	IMP	J:130925
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-3965440
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-517516
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:130925
Cellular Component	GO:0045202	synapse	IDA	J:263445
Cellular Component	GO:0045202	synapse	IDA	J:263445
Biological Process	GO:0001525	angiogenesis	IGI	J:239107
Biological Process	GO:0001525	angiogenesis	IMP	J:239107
Biological Process	GO:0001568	blood vessel development	IMP	J:154020
Biological Process	GO:0060070	canonical Wnt signaling pathway	ISO	J:164563
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:227384
Biological Process	GO:0060070	canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:101493
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:101493
Biological Process	GO:0060070	canonical Wnt signaling pathway	IGI	J:106895
Biological Process	GO:0008283	cell population proliferation	IMP	J:230295
Biological Process	GO:0007166	cell surface receptor signaling pathway	IEA	J:72247
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0061301	cerebellum vasculature morphogenesis	IMP	J:107732
Biological Process	GO:0045446	endothelial cell differentiation	IMP	J:193332
Biological Process	GO:0060856	establishment of blood-brain barrier	IMP	J:193332
Biological Process	GO:0060856	establishment of blood-brain barrier	IGI	J:269489
Biological Process	GO:0035426	extracellular matrix-cell signaling	IDA	J:107732
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:60000
Biological Process	GO:0031987	locomotion involved in locomotory behavior	IMP	J:70078
Biological Process	GO:0001553	luteinization	IMP	J:115734
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	ISO	J:164563
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	IMP	J:130925
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	IBA	J:265628
Biological Process	GO:0110135	Norrin signaling pathway	ISO	J:164563
Biological Process	GO:0110135	Norrin signaling pathway	IDA	J:107732
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	ISO	J:155856
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	ISO	J:164563
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:107732
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:107732
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0043507	positive regulation of JUN kinase activity	IGI	J:163736
Biological Process	GO:0150012	positive regulation of neuron projection arborization	IGI	J:255327
Biological Process	GO:0150012	positive regulation of neuron projection arborization	ISO	J:155856
Biological Process	GO:0042701	progesterone secretion	IMP	J:115734
Biological Process	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	IMP	J:115734
Biological Process	GO:0001666	response to hypoxia	IMP	J:230295
Biological Process	GO:0061298	retina vasculature development in camera-type eye	IMP	J:193332
Biological Process	GO:0061298	retina vasculature development in camera-type eye	IMP	J:215763
Biological Process	GO:0061298	retina vasculature development in camera-type eye	IMP	J:230295
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	ISO	J:164563
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	IBA	J:265628
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	IMP	J:154020
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	IGI	J:154020
Biological Process	GO:0061299	retina vasculature morphogenesis in camera-type eye	IGI	J:154020
Biological Process	GO:0061304	retinal blood vessel morphogenesis	IMP	J:107732
Biological Process	GO:0007605	sensory perception of sound	IMP	J:70078
Biological Process	GO:0007165	signal transduction	IEA	J:60000
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	IMP	J:130925
Biological Process	GO:0001570	vasculogenesis	IMP	J:115734
Biological Process	GO:0016055	Wnt signaling pathway	IGI	J:255327
Biological Process	GO:0016055	Wnt signaling pathway	ISO	J:155856
Biological Process	GO:0007223	Wnt signaling pathway, calcium modulating pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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