GO Annotations Graph

• Symbol: Prkag1
• Name: protein kinase, AMP-activated, gamma 1 non-catalytic subunit
• ID: MGI:108411

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0032559	adenyl ribonucleotide binding	IEA	J:72247
Molecular Function	GO:0043531	ADP binding	ISO	J:155856
Molecular Function	GO:0016208	AMP binding	ISO	J:155856
Molecular Function	GO:0004679	AMP-activated protein kinase activity	ISO	J:155856
Molecular Function	GO:0004679	AMP-activated protein kinase activity	TAS	J:54164
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:108933
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0019887	protein kinase regulator activity	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1454711
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9613545
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-1605475
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	ISO	J:155856
Cellular Component	GO:0031588	nucleotide-activated protein kinase complex	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:54164
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:164563
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:320114
Biological Process	GO:0031669	cellular response to nutrient levels	NAS	J:320077
Biological Process	GO:0006633	fatty acid biosynthetic process	IEA	J:60000
Biological Process	GO:0006631	fatty acid metabolic process	IEA	J:60000
Biological Process	GO:0051170	import into nucleus	IMP	J:236948
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0050790	regulation of catalytic activity	ISO	J:155856
Biological Process	GO:0071900	regulation of protein serine/threonine kinase activity	IEA	J:72247