GO Annotations Graph

• Symbol: Ext2
• Name: exostosin glycosyltransferase 2
• ID: MGI:108050

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008375	acetylglucosaminyltransferase activity	ISO	J:164563
Molecular Function	GO:0008375	acetylglucosaminyltransferase activity	IDA	J:113870
Molecular Function	GO:0008375	acetylglucosaminyltransferase activity	IBA	J:265628
Molecular Function	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	IC	J:113870
Molecular Function	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	IGI	J:113870
Molecular Function	GO:0015020	glucuronosyltransferase activity	ISO	J:164563
Molecular Function	GO:0015020	glucuronosyltransferase activity	IDA	J:113870
Molecular Function	GO:0016757	glycosyltransferase activity	ISO	J:164563
Molecular Function	GO:0042328	heparan sulfate N-acetylglucosaminyltransferase activity	IC	J:113870
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	IC	J:113870
Molecular Function	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	IBA	J:265628
Molecular Function	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	IGI	J:113870
Molecular Function	GO:0005515	protein binding	IPI	J:133353
Molecular Function	GO:0046982	protein heterodimerization activity	ISO	J:164563
Molecular Function	GO:0042803	protein homodimerization activity	IDA	J:113870
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:113870
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IC	J:113870
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:113870
Cellular Component	GO:0000139	Golgi membrane	IC	J:113870
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043541	UDP-N-acetylglucosamine transferase complex	ISO	J:164563
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	IMP	J:286741
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:103125
Biological Process	GO:0060350	endochondral bone morphogenesis	IGI	J:286741
Biological Process	GO:0042044	fluid transport	IGI	J:279714
Biological Process	GO:0010467	gene expression	IMP	J:133353
Biological Process	GO:0010467	gene expression	IDA	J:133353
Biological Process	GO:0006024	glycosaminoglycan biosynthetic process	ISO	J:164563
Biological Process	GO:0060047	heart contraction	IGI	J:279714
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	ISO	J:164563
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IGI	J:113870
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IMP	J:103125
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	IMP	J:103125
Biological Process	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	ISO	J:164563
Biological Process	GO:0030210	heparin biosynthetic process	IGI	J:286741
Biological Process	GO:0001707	mesoderm formation	IMP	J:103125
Biological Process	GO:0001707	mesoderm formation	IMP	J:103125
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	IGI	J:279714
Biological Process	GO:0001503	ossification	ISO	J:164563
Biological Process	GO:0000271	polysaccharide biosynthetic process	ISO	J:164563
Biological Process	GO:0006486	protein glycosylation	IEA	J:72247
Biological Process	GO:0006487	protein N-linked glycosylation	IDA	J:133353
Biological Process	GO:0008217	regulation of blood pressure	IGI	J:279714
Biological Process	GO:0055078	sodium ion homeostasis	IGI	J:279714
Biological Process	GO:0051923	sulfation	IDA	J:133353
Biological Process	GO:0042311	vasodilation	IGI	J:279714