GO Annotations Graph

• Symbol: Pip5k1a
• Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
• ID: MGI:107929

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	IMP	J:265618
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	ISO	J:164563
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	IDA	J:35632
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	IGI	J:166299
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0016307	phosphatidylinositol phosphate kinase activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:88739
Molecular Function	GO:0005515	protein binding	IPI	J:99138
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:166299
Cellular Component	GO:0030027	lamellipodium	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	ISO	J:164563
Cellular Component	GO:0016607	nuclear speck	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:99138
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Cellular Component	GO:0032587	ruffle membrane	IDA	J:99138
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0090630	activation of GTPase activity	ISO	J:164563
Biological Process	GO:0060326	cell chemotaxis	ISO	J:164563
Biological Process	GO:0010761	fibroblast migration	IMP	J:99138
Biological Process	GO:0048041	focal adhesion assembly	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0046834	lipid phosphorylation	IDA	J:35632
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	IGI	J:166299
Biological Process	GO:0046488	phosphatidylinositol metabolic process	IDA	J:35632
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	IDA	J:35632
Biological Process	GO:0008654	phospholipid biosynthetic process	ISO	J:164563
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0072659	protein localization to plasma membrane	ISO	J:164563
Biological Process	GO:0097178	ruffle assembly	ISO	J:164563