GO Annotations Graph

• Symbol: Myh9
• Name: myosin, heavy polypeptide 9, non-muscle
• ID: MGI:107717

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:73065
Molecular Function	GO:0051015	actin filament binding	IBA	J:265628
Molecular Function	GO:0051015	actin filament binding	ISO	J:73065
Molecular Function	GO:0043531	ADP binding	ISO	J:73065
Molecular Function	GO:0005524	ATP binding	ISO	J:73065
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0003774	cytoskeletal motor activity	IEA	J:72247
Molecular Function	GO:0031762	follicle-stimulating hormone receptor binding	ISO	J:155856
Molecular Function	GO:0001965	G-protein alpha-subunit binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0005178	integrin binding	ISO	J:164563
Molecular Function	GO:0000146	microfilament motor activity	IBA	J:265628
Molecular Function	GO:0000146	microfilament motor activity	ISO	J:73065
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:222132
Molecular Function	GO:0005515	protein binding	IPI	J:174152
Molecular Function	GO:0005515	protein binding	IPI	J:105078
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:219057
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0043495	protein-membrane adaptor activity	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:155856
Cellular Component	GO:0015629	actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005884	actin filament	ISO	J:155856
Cellular Component	GO:0042641	actomyosin	ISO	J:164563
Cellular Component	GO:0005826	actomyosin contractile ring	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:94940
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0005903	brush border	ISO	J:155856
Cellular Component	GO:0005938	cell cortex	IDA	J:278740
Cellular Component	GO:0005938	cell cortex	IDA	J:113128
Cellular Component	GO:0005938	cell cortex	IDA	J:49882
Cellular Component	GO:0031252	cell leading edge	ISO	J:164563
Cellular Component	GO:0032154	cleavage furrow	ISO	J:164563
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0030863	cortical cytoskeleton	IDA	J:92230
Cellular Component	GO:0060473	cortical granule	IDA	J:278740
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:94067
Cellular Component	GO:0005737	cytoplasm	IDA	J:90712
Cellular Component	GO:0005737	cytoplasm	IDA	J:94067
Cellular Component	GO:0005737	cytoplasm	IDA	J:94940
Cellular Component	GO:0005737	cytoplasm	IDA	J:49882
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	ISO	J:73065
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	IDA	J:113128
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9659536
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9663360
Cellular Component	GO:0005768	endosome	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	IDA	J:219057
Cellular Component	GO:0001772	immunological synapse	IDA	J:89810
Cellular Component	GO:0001772	immunological synapse	ISO	J:73065
Cellular Component	GO:0030027	lamellipodium	ISO	J:155856
Cellular Component	GO:0016328	lateral plasma membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:44181
Cellular Component	GO:0016459	myosin complex	IDA	J:44181
Cellular Component	GO:0016459	myosin complex	IDA	J:49882
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0016459	myosin complex	IDA	J:44181
Cellular Component	GO:0016459	myosin complex	IDA	J:45687
Cellular Component	GO:0032982	myosin filament	IBA	J:265628
Cellular Component	GO:0016460	myosin II complex	ISO	J:164563
Cellular Component	GO:0016460	myosin II complex	IBA	J:265628
Cellular Component	GO:0016460	myosin II complex	IDA	J:168709
Cellular Component	GO:0097513	myosin II filament	ISO	J:164563
Cellular Component	GO:0031594	neuromuscular junction	IDA	J:103681
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0045335	phagocytic vesicle	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Cellular Component	GO:0005819	spindle	IDA	J:49882
Cellular Component	GO:0001725	stress fiber	ISO	J:73065
Cellular Component	GO:0001725	stress fiber	IDA	J:113128
Cellular Component	GO:0001931	uropod	IDA	J:89810
Cellular Component	GO:0001931	uropod	ISO	J:73065
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0031532	actin cytoskeleton reorganization	ISO	J:155856
Biological Process	GO:0051017	actin filament bundle assembly	ISO	J:155856
Biological Process	GO:0070650	actin filament bundle distribution	ISO	J:155856
Biological Process	GO:0030048	actin filament-based movement	ISO	J:73065
Biological Process	GO:0031032	actomyosin structure organization	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	ISO	J:164563
Biological Process	GO:0043534	blood vessel endothelial cell migration	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IMP	J:105078
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	IMP	J:94940
Biological Process	GO:0098609	cell-cell adhesion	ISO	J:155856
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:94940
Biological Process	GO:0060471	cortical granule exocytosis	IMP	J:278740
Biological Process	GO:0032506	cytokinetic process	ISO	J:164563
Biological Process	GO:0051295	establishment of meiotic spindle localization	IDA	J:49882
Biological Process	GO:0001768	establishment of T cell polarity	IMP	J:89810
Biological Process	GO:0042699	follicle-stimulating hormone signaling pathway	ISO	J:155856
Biological Process	GO:0001701	in utero embryonic development	IMP	J:94067
Biological Process	GO:0001701	in utero embryonic development	IMP	J:110432
Biological Process	GO:0032418	lysosome localization	ISO	J:164563
Biological Process	GO:0000212	meiotic spindle organization	IDA	J:49882
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	ISO	J:164563
Biological Process	GO:0007520	myoblast fusion	IMP	J:113128
Biological Process	GO:1903919	negative regulation of actin filament severing	ISO	J:164563
Biological Process	GO:1903919	negative regulation of actin filament severing	IMP	J:219057
Biological Process	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0006911	phagocytosis, engulfment	IMP	J:219057
Biological Process	GO:0001778	plasma membrane repair	ISO	J:164563
Biological Process	GO:0030220	platelet formation	ISO	J:164563
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	ISO	J:155856
Biological Process	GO:0045807	positive regulation of endocytosis	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	ISO	J:155856
Biological Process	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process	ISO	J:155856
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:0050766	positive regulation of phagocytosis	ISO	J:155856
Biological Process	GO:1903923	positive regulation of protein processing in phagocytic vesicle	IMP	J:219057
Biological Process	GO:0015031	protein transport	ISO	J:164563
Biological Process	GO:0045055	regulated exocytosis	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	IMP	J:113128
Biological Process	GO:1905684	regulation of plasma membrane repair	ISO	J:164563
Biological Process	GO:0032796	uropod organization	IMP	J:89810