GO Annotations Graph

• Symbol: Plxna2
• Name: plexin A2
• ID: MGI:107684

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	IPI	J:180543
Molecular Function	GO:0042802	identical protein binding	IPI	J:180544
Molecular Function	GO:0005515	protein binding	IPI	J:180543
Molecular Function	GO:0005515	protein binding	IPI	J:245348
Molecular Function	GO:0005515	protein binding	IPI	J:180544
Molecular Function	GO:0017154	semaphorin receptor activity	IMP	J:180544
Molecular Function	GO:0017154	semaphorin receptor activity	IBA	J:265628
Molecular Function	GO:0017154	semaphorin receptor activity	IPI	J:135408
Molecular Function	GO:0017154	semaphorin receptor activity	IGI	J:135408
Molecular Function	GO:0017154	semaphorin receptor activity	IGI	J:135408
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:265607
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:180543
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2045917
Cellular Component	GO:0002116	semaphorin receptor complex	IBA	J:265628
Biological Process	GO:0007166	cell surface receptor signaling pathway	IDA	J:135408
Biological Process	GO:0051642	centrosome localization	IMP	J:135408
Biological Process	GO:0021935	cerebellar granule cell precursor tangential migration	IMP	J:135408
Biological Process	GO:0021935	cerebellar granule cell precursor tangential migration	IMP	J:135408
Biological Process	GO:0060174	limb bud formation	IEP	J:151961
Biological Process	GO:0007162	negative regulation of cell adhesion	IBA	J:265628
Biological Process	GO:0021915	neural tube development	IEP	J:151961
Biological Process	GO:0060037	pharyngeal system development	IEP	J:151961
Biological Process	GO:0050772	positive regulation of axonogenesis	IBA	J:265628
Biological Process	GO:0030334	regulation of cell migration	IMP	J:180544
Biological Process	GO:0030334	regulation of cell migration	IBA	J:265628
Biological Process	GO:0008360	regulation of cell shape	IBA	J:265628
Biological Process	GO:0043087	regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IPI	J:135408
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IMP	J:180544
Biological Process	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	IBA	J:265628
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0001756	somitogenesis	IEP	J:151961