GO Annotations Graph

• Symbol: Slc5a1
• Name: solute carrier family 5 (sodium/glucose cotransporter), member 1
• ID: MGI:107678

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015151	alpha-glucoside transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0055056	D-glucose transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0015371	galactose:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0005355	glucose transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005355	glucose transmembrane transporter activity	IMP	J:65175
Molecular Function	GO:0005412	glucose:sodium symporter activity	ISO	J:155856
Molecular Function	GO:0005412	glucose:sodium symporter activity	IDA	J:186790
Molecular Function	GO:0005412	glucose:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005412	glucose:sodium symporter activity	ISO	J:73065
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Molecular Function	GO:0022857	transmembrane transporter activity	IEA	J:72247
Molecular Function	GO:0005372	water transmembrane transporter activity	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:186790
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:35094
Cellular Component	GO:0005903	brush border	IDA	J:95148
Cellular Component	GO:0031526	brush border membrane	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:164563
Cellular Component	GO:0043229	intracellular organelle	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Biological Process	GO:0000017	alpha-glucoside transport	ISO	J:164563
Biological Process	GO:0008643	carbohydrate transport	IEA	J:60000
Biological Process	GO:0098708	glucose import across plasma membrane	ISO	J:164563
Biological Process	GO:1904659	glucose transmembrane transport	IMP	J:65175
Biological Process	GO:1904659	glucose transmembrane transport	ISO	J:73065
Biological Process	GO:0050892	intestinal absorption	IDA	J:95148
Biological Process	GO:0001951	intestinal D-glucose absorption	IMP	J:186790
Biological Process	GO:0001656	metanephros development	IMP	J:65175
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0032409	regulation of transporter activity	IDA	J:258659
Biological Process	GO:0035623	renal glucose absorption	IMP	J:186790
Biological Process	GO:0010035	response to inorganic substance	ISO	J:164563
Biological Process	GO:0098719	sodium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0006814	sodium ion transport	IBA	J:265628
Biological Process	GO:0035377	transepithelial water transport	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0150104	transport across blood-brain barrier	ISO	J:164563