GO Annotations Graph

• Symbol: Ifnb1
• Name: interferon beta 1, fibroblast
• ID: MGI:107657

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008811	chloramphenicol O-acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	ISO	J:164563
Molecular Function	GO:0005125	cytokine activity	IBA	J:265628
Molecular Function	GO:0005125	cytokine activity	IDA	J:91936
Molecular Function	GO:0005126	cytokine receptor binding	ISO	J:164563
Molecular Function	GO:0005132	type I interferon receptor binding	IPI	J:208239
Molecular Function	GO:0005132	type I interferon receptor binding	IBA	J:265628
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-912695
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	ISO	J:280922
Cellular Component	GO:0005615	extracellular space	IDA	J:143981
Biological Process	GO:0002250	adaptive immune response	IBA	J:265628
Biological Process	GO:0002250	adaptive immune response	IDA	J:143981
Biological Process	GO:0002312	B cell activation involved in immune response	ISO	J:164563
Biological Process	GO:0030183	B cell differentiation	IBA	J:265628
Biological Process	GO:0042100	B cell proliferation	IMP	J:86527
Biological Process	GO:0042100	B cell proliferation	IBA	J:265628
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	IDA	J:173334
Biological Process	GO:0071359	cellular response to dsRNA	IEP	J:140892
Biological Process	GO:0035458	cellular response to interferon-beta	ISO	J:164563
Biological Process	GO:0098586	cellular response to virus	IDA	J:222665
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0006952	defense response	IEA	J:72247
Biological Process	GO:0042742	defense response to bacterium	IDA	J:91936
Biological Process	GO:0051607	defense response to virus	IMP	J:235021
Biological Process	GO:0051607	defense response to virus	IDA	J:61048
Biological Process	GO:0051607	defense response to virus	IDA	J:143981
Biological Process	GO:0006959	humoral immune response	IBA	J:265628
Biological Process	GO:0006959	humoral immune response	IDA	J:143981
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0002281	macrophage activation involved in immune response	ISO	J:155856
Biological Process	GO:0002323	natural killer cell activation involved in immune response	IBA	J:265628
Biological Process	GO:0140123	negative regulation of Lewy body formation	IMP	J:226090
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	IDA	J:145836
Biological Process	GO:0045581	negative regulation of T cell differentiation	ISO	J:164563
Biological Process	GO:2000552	negative regulation of T-helper 2 cell cytokine production	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:226090
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0010508	positive regulation of autophagy	IMP	J:226090
Biological Process	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	ISO	J:164563
Biological Process	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	ISO	J:164563
Biological Process	GO:0043330	response to exogenous dsRNA	IBA	J:265628
Biological Process	GO:0043330	response to exogenous dsRNA	ISO	J:170947
Biological Process	GO:0002286	T cell activation involved in immune response	IBA	J:265628
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	IMP	J:235021
Biological Process	GO:0060337	type I interferon-mediated signaling pathway	ISO	J:164563