GO Annotations Graph

• Symbol: Cav2
• Name: caveolin 2
• ID: MGI:107571

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031748	D1 dopamine receptor binding	ISS	J:154838
Molecular Function	GO:0031748	D1 dopamine receptor binding	ISO	J:164563
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	IDA	J:217289
Molecular Function	GO:0060090	molecular adaptor activity	IBA	J:265628
Molecular Function	GO:0051219	phosphoprotein binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:126756
Molecular Function	GO:0046982	protein heterodimerization activity	IPI	J:217293
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:73065
Molecular Function	GO:0019901	protein kinase binding	IDA	J:217289
Molecular Function	GO:0019901	protein kinase binding	IPI	J:217289
Molecular Function	GO:0019901	protein kinase binding	IBA	J:265628
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IDA	J:217289
Molecular Function	GO:0097110	scaffold protein binding	IPI	J:217289
Molecular Function	GO:0000149	SNARE binding	ISO	J:155856
Molecular Function	GO:0019905	syntaxin binding	ISO	J:155856
Cellular Component	GO:0002080	acrosomal membrane	IDA	J:149637
Cellular Component	GO:0005901	caveola	ISS	J:154836
Cellular Component	GO:0005901	caveola	ISO	J:155856
Cellular Component	GO:0005901	caveola	ISO	J:164563
Cellular Component	GO:0005901	caveola	ISO	J:73065
Cellular Component	GO:0005901	caveola	ISO	J:201740
Cellular Component	GO:0005901	caveola	IDA	J:75490
Cellular Component	GO:0002095	caveolar macromolecular signaling complex	IDA	J:75490
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IBA	J:265628
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:189648
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	ISO	J:164563
Cellular Component	GO:0005925	focal adhesion	IDA	J:217289
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IBA	J:265628
Cellular Component	GO:0005811	lipid droplet	ISO	J:155856
Cellular Component	GO:0016020	membrane	IDA	J:167702
Cellular Component	GO:0045121	membrane raft	ISO	J:164563
Cellular Component	GO:0045121	membrane raft	ISO	J:155856
Cellular Component	GO:0005635	nuclear envelope	ISO	J:155856
Cellular Component	GO:0005637	nuclear inner membrane	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISS	J:154898
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0048471	perinuclear region of cytoplasm	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:100274
Cellular Component	GO:0005886	plasma membrane	IDA	J:79453
Cellular Component	GO:0005886	plasma membrane	ISO	J:73065
Cellular Component	GO:0005886	plasma membrane	IDA	J:79453
Cellular Component	GO:0005886	plasma membrane	IDA	J:75490
Cellular Component	GO:0044853	plasma membrane raft	ISS	J:154838
Cellular Component	GO:0044853	plasma membrane raft	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IDA	J:217289
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:201740
Cellular Component	GO:0042383	sarcolemma	IBA	J:265628
Cellular Component	GO:0030133	transport vesicle	ISO	J:164563
Biological Process	GO:0071711	basement membrane organization	IMP	J:75490
Biological Process	GO:0070836	caveola assembly	ISS	J:154845
Biological Process	GO:0070836	caveola assembly	ISO	J:164563
Biological Process	GO:0070836	caveola assembly	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0008283	cell population proliferation	IMP	J:117199
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0006897	endocytosis	TAS	J:55894
Biological Process	GO:0007029	endoplasmic reticulum organization	IMP	J:117199
Biological Process	GO:0001935	endothelial cell proliferation	IMP	J:75490
Biological Process	GO:0001935	endothelial cell proliferation	IGI	J:178359
Biological Process	GO:0001935	endothelial cell proliferation	IGI	J:178359
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:155856
Biological Process	GO:0008286	insulin receptor signaling pathway	ISO	J:164563
Biological Process	GO:0008286	insulin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007005	mitochondrion organization	IMP	J:117199
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	ISO	J:155856
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	IBA	J:265628
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	IMP	J:75490
Biological Process	GO:0014859	negative regulation of skeletal muscle cell proliferation	IMP	J:117199
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IGI	J:178359
Biological Process	GO:0044794	positive regulation by host of viral process	ISO	J:164563
Biological Process	GO:0060161	positive regulation of dopamine receptor signaling pathway	ISS	J:154838
Biological Process	GO:0060161	positive regulation of dopamine receptor signaling pathway	ISO	J:164563
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	IGI	J:178359
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:164563
Biological Process	GO:0043410	positive regulation of MAPK cascade	ISO	J:155856
Biological Process	GO:0043410	positive regulation of MAPK cascade	IBA	J:265628
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ISO	J:155856
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:155856
Biological Process	GO:0019065	receptor-mediated endocytosis of virus by host cell	ISO	J:164563
Biological Process	GO:0051480	regulation of cytosolic calcium ion concentration	IBA	J:265628
Biological Process	GO:0014856	skeletal muscle cell proliferation	IMP	J:117199
Biological Process	GO:0048741	skeletal muscle fiber development	IMP	J:117199
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:178359
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IGI	J:178359
Biological Process	GO:0048278	vesicle docking	ISS	J:154843
Biological Process	GO:0048278	vesicle docking	ISO	J:164563
Biological Process	GO:0006906	vesicle fusion	ISS	J:154843
Biological Process	GO:0006906	vesicle fusion	ISO	J:164563
Biological Process	GO:0016050	vesicle organization	ISO	J:164563
Biological Process	GO:0019076	viral release from host cell	ISO	J:164563