GO Annotations Graph

• Symbol: Zic2
• Name: zinc finger protein of the cerebellum 2
• ID: MGI:106679

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031490	chromatin DNA binding	IDA	J:164404
Molecular Function	GO:0003677	DNA binding	IDA	J:130327
Molecular Function	GO:0003677	DNA binding	IDA	J:93136
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:169807
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:93136
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:130327
Molecular Function	GO:0005515	protein binding	IPI	J:114033
Molecular Function	GO:0005515	protein binding	IPI	J:169910
Molecular Function	GO:0005515	protein binding	IPI	J:93136
Molecular Function	GO:0005515	protein binding	IPI	J:170532
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:169807
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:136993
Cellular Component	GO:0005737	cytoplasm	IDA	J:169910
Cellular Component	GO:0005737	cytoplasm	IDA	J:93136
Cellular Component	GO:0005737	cytoplasm	IDA	J:143129
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:169910
Cellular Component	GO:0005634	nucleus	IDA	J:114033
Cellular Component	GO:0005634	nucleus	IDA	J:130327
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:143129
Cellular Component	GO:0005634	nucleus	IDA	J:84357
Cellular Component	GO:0005634	nucleus	IDA	J:93136
Biological Process	GO:0048318	axial mesoderm development	IGI	J:122556
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IBA	J:265628
Biological Process	GO:0007417	central nervous system development	IGI	J:73494
Biological Process	GO:0035283	central nervous system segmentation	IGI	J:122556
Biological Process	GO:0044782	cilium organization	IMP	J:213344
Biological Process	GO:0048066	developmental pigmentation	IMP	J:63816
Biological Process	GO:0010467	gene expression	IMP	J:170532
Biological Process	GO:0010467	gene expression	IGI	J:122556
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:169807
Biological Process	GO:0007399	nervous system development	IMP	J:60644
Biological Process	GO:0014033	neural crest cell differentiation	IMP	J:93195
Biological Process	GO:0001840	neural plate development	IGI	J:122556
Biological Process	GO:0001843	neural tube closure	IMP	J:93195
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:122556
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	IDA	J:164404
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:93136
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:164404
Biological Process	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	IMP	J:213344
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:169807
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0031290	retinal ganglion cell axon guidance	IMP	J:85445
Biological Process	GO:0007601	visual perception	IMP	J:85445
Biological Process	GO:0007601	visual perception	IMP	J:164404