GO Annotations Graph

• Symbol: Hells
• Name: helicase, lymphoid specific
• ID: MGI:106209

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0140658	ATP-dependent chromatin remodeler activity	IEA	J:72247
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:93871
Molecular Function	GO:0004386	helicase activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:248225
Molecular Function	GO:0005515	protein binding	IPI	J:200300
Cellular Component	GO:0000775	chromosome, centromeric region	IDA	J:89936
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:71817
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:89936
Cellular Component	GO:0005721	pericentric heterochromatin	IBA	J:265628
Biological Process	GO:0006915	apoptotic process	IMP	J:76112
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0006306	DNA methylation	IBA	J:265628
Biological Process	GO:0006306	DNA methylation	IMP	J:72618
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IMP	J:96925
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IBA	J:265628
Biological Process	GO:0031507	heterochromatin formation	IMP	J:93871
Biological Process	GO:0001822	kidney development	IMP	J:76112
Biological Process	GO:0030098	lymphocyte differentiation	TAS	J:76112
Biological Process	GO:0046651	lymphocyte proliferation	IEP	J:61948
Biological Process	GO:0046651	lymphocyte proliferation	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:76112
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	IMP	J:107145
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	IBA	J:265628
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	IMP	J:76112
Biological Process	GO:0031508	pericentric heterochromatin formation	IMP	J:89936
Biological Process	GO:0031508	pericentric heterochromatin formation	IBA	J:265628
Biological Process	GO:0001655	urogenital system development	IMP	J:76112