About   Help   FAQ
GO Annotations Graph
Symbol
Name
ID
Ccr2
chemokine (C-C motif) receptor 2
MGI:106185

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0016493C-C chemokine receptor activityIDAJ:33019
Molecular FunctionGO:0016493C-C chemokine receptor activityIDAJ:32263
Molecular FunctionGO:0035716chemokine (C-C motif) ligand 12 bindingIPIJ:37573
Molecular FunctionGO:0035715chemokine (C-C motif) ligand 2 bindingIPIJ:33019
Molecular FunctionGO:0035717chemokine (C-C motif) ligand 7 bindingIPIJ:33019
Molecular FunctionGO:0004950chemokine receptor activityIEAJ:72247
Molecular FunctionGO:0019955cytokine bindingIPIJ:32263
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:72247
Molecular FunctionGO:0004930G-protein coupled receptor activityIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:33019
Molecular FunctionGO:0004871signal transducer activityIEAJ:60000
Cellular ComponentGO:0009897external side of plasma membraneIDAJ:197348
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneTASJ:159685
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0005886plasma membraneISAJ:100459
Biological ProcessGO:0001525angiogenesisTASJ:169885
Biological ProcessGO:0043277apoptotic cell clearanceICJ:33019
Biological ProcessGO:0001974blood vessel remodelingIEAJ:72247
Biological ProcessGO:0006968cellular defense responseIMPJ:44345
Biological ProcessGO:0019725cellular homeostasisIDAJ:140759
Biological ProcessGO:0006935chemotaxisIEAJ:72247
Biological ProcessGO:0019221cytokine-mediated signaling pathwayISAJ:100459
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayIEAJ:72247
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayIEAJ:60000
Biological ProcessGO:0030097hemopoiesisIMPJ:44345
Biological ProcessGO:0006959humoral immune responseIMPJ:63491
Biological ProcessGO:0006955immune responseIMPJ:64054
Biological ProcessGO:0006955immune responseIMPJ:64904
Biological ProcessGO:0006955immune responseIMPJ:62675
Biological ProcessGO:0006954inflammatory responseIMPJ:64054
Biological ProcessGO:0002548monocyte chemotaxisIMPJ:208234
Biological ProcessGO:0016525negative regulation of angiogenesisIMPJ:147328
Biological ProcessGO:0043310negative regulation of eosinophil degranulationIMPJ:118487
Biological ProcessGO:0002829negative regulation of type 2 immune responseIMPJ:118487
Biological ProcessGO:0046641positive regulation of alpha-beta T cell proliferationIMPJ:118487
Biological ProcessGO:2000464positive regulation of astrocyte chemotaxisISOJ:164563
Biological ProcessGO:2000451positive regulation of CD8-positive, alpha-beta T cell extravasationIMPJ:118487
Biological ProcessGO:2000473positive regulation of hematopoietic stem cell migrationIMPJ:159685
Biological ProcessGO:0090265positive regulation of immune complex clearance by monocytes and macrophagesIMPJ:147328
Biological ProcessGO:0050729positive regulation of inflammatory responseIDAJ:159685
Biological ProcessGO:0032729positive regulation of interferon-gamma productionIMPJ:118487
Biological ProcessGO:0032743positive regulation of interleukin-2 productionIMPJ:118487
Biological ProcessGO:0090026positive regulation of monocyte chemotaxisISOJ:164563
Biological ProcessGO:0090026positive regulation of monocyte chemotaxisIMPJ:140759
Biological ProcessGO:2000439positive regulation of monocyte extravasationIMPJ:147328
Biological ProcessGO:0050870positive regulation of T cell activationIMPJ:118487
Biological ProcessGO:0010820positive regulation of T cell chemotaxisIDAJ:140232
Biological ProcessGO:0045627positive regulation of T-helper 1 cell differentiationICJ:118487
Biological ProcessGO:0002827positive regulation of T-helper 1 type immune responseIMPJ:125574
Biological ProcessGO:0042535positive regulation of tumor necrosis factor biosynthetic processIMPJ:140759
Biological ProcessGO:0030334regulation of cell migrationIMPJ:64904
Biological ProcessGO:0030334regulation of cell migrationIMPJ:62675
Biological ProcessGO:0030334regulation of cell migrationIMPJ:63491
Biological ProcessGO:0010574regulation of vascular endothelial growth factor productionIMPJ:147328
Biological ProcessGO:0019233sensory perception of painIMPJ:84630
Biological ProcessGO:0007165signal transductionIEAJ:60000
Biological ProcessGO:0035705T-helper 17 cell chemotaxisIDAJ:140232
Biological ProcessGO:0002246wound healing involved in inflammatory responseNASJ:159685


Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory