GO Annotations Graph

• Symbol: Adcyap1
• Name: adenylate cyclase activating polypeptide 1
• ID: MGI:105094

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005179	hormone activity	IEA	J:72247
Molecular Function	GO:0005179	hormone activity	IEA	J:60000
Molecular Function	GO:0005184	neuropeptide hormone activity	ISO	J:155856
Molecular Function	GO:0005184	neuropeptide hormone activity	ISO	J:164563
Molecular Function	GO:0005184	neuropeptide hormone activity	IBA	J:265628
Molecular Function	GO:0005184	neuropeptide hormone activity	TAS	J:49214
Molecular Function	GO:0051428	peptide hormone receptor binding	ISO	J:164563
Molecular Function	GO:0051428	peptide hormone receptor binding	IBA	J:265628
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	ISO	J:164563
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	ISO	J:155856
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	IDA	J:183231
Molecular Function	GO:0016521	pituitary adenylate cyclase activating polypeptide activity	IBA	J:265628
Molecular Function	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding	ISO	J:155856
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IBA	J:265628
Cellular Component	GO:0043204	perikaryon	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	ISO	J:155856
Biological Process	GO:0007190	activation of adenylate cyclase activity	TAS	J:49214
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:155856
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	J:183231
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA	J:265628
Biological Process	GO:0046034	ATP metabolic process	ISO	J:155856
Biological Process	GO:0001662	behavioral fear response	ISO	J:155856
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:164563
Biological Process	GO:0019933	cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IEA	J:72247
Biological Process	GO:0001821	histamine secretion	ISO	J:155856
Biological Process	GO:0030073	insulin secretion	IDA	J:203279
Biological Process	GO:0002865	negative regulation of acute inflammatory response to antigenic stimulus	ISO	J:155856
Biological Process	GO:0002878	negative regulation of acute inflammatory response to non-antigenic stimulus	ISO	J:155856
Biological Process	GO:0045786	negative regulation of cell cycle	IDA	J:79998
Biological Process	GO:0060253	negative regulation of glial cell proliferation	ISO	J:155856
Biological Process	GO:0034260	negative regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0010656	negative regulation of muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0043267	negative regulation of potassium ion transport	ISO	J:155856
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	ISO	J:155856
Biological Process	GO:0031175	neuron projection development	ISO	J:164563
Biological Process	GO:0031175	neuron projection development	IBA	J:265628
Biological Process	GO:0007218	neuropeptide signaling pathway	ISO	J:155856
Biological Process	GO:0007218	neuropeptide signaling pathway	ISO	J:164563
Biological Process	GO:0007218	neuropeptide signaling pathway	IBA	J:265628
Biological Process	GO:0007218	neuropeptide signaling pathway	TAS	J:49214
Biological Process	GO:0001541	ovarian follicle development	ISO	J:155856
Biological Process	GO:0043950	positive regulation of cAMP-mediated signaling	ISO	J:155856
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production	ISO	J:164563
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	IMP	J:79468
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:155856
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	IBA	J:265628
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:203279
Biological Process	GO:0060124	positive regulation of growth hormone secretion	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:155856
Biological Process	GO:0043547	positive regulation of GTPase activity	IBA	J:265628
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:155856
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:155856
Biological Process	GO:0045860	positive regulation of protein kinase activity	IBA	J:265628
Biological Process	GO:0090274	positive regulation of somatostatin secretion	ISO	J:155856
Biological Process	GO:0051968	positive regulation of synaptic transmission, glutamatergic	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	ISO	J:164563
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	ISO	J:155856
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	IDA	J:183231
Biological Process	GO:0032880	regulation of protein localization	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	ISO	J:155856
Biological Process	GO:0032880	regulation of protein localization	IBA	J:265628
Biological Process	GO:0001932	regulation of protein phosphorylation	ISO	J:155856
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0042311	vasodilation	ISO	J:155856