Nfkbia GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
MGI:104741

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:155856
Molecular Function	GO:0051059	NF-kappaB binding	IBA	J:265628
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:73065
Molecular Function	GO:0008139	nuclear localization sequence binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:175173
Molecular Function	GO:0005515	protein binding	IPI	J:75267
Molecular Function	GO:0005515	protein binding	IPI	J:201834
Molecular Function	GO:0005515	protein binding	IPI	J:114108
Molecular Function	GO:0005515	protein binding	IPI	J:116423
Molecular Function	GO:0005515	protein binding	IPI	J:163302
Molecular Function	GO:0005515	protein binding	IPI	J:245288
Molecular Function	GO:0005515	protein binding	IPI	J:197511
Molecular Function	GO:0005515	protein binding	IPI	J:190685
Molecular Function	GO:0005515	protein binding	IPI	J:190685
Molecular Function	GO:0005515	protein binding	IPI	J:200399
Molecular Function	GO:0005515	protein binding	IPI	J:75464
Molecular Function	GO:0005515	protein binding	IPI	J:41993
Molecular Function	GO:0140311	protein sequestering activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:75464
Cellular Component	GO:0005737	cytoplasm	IDA	J:176455
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:150450
Cellular Component	GO:0005829	cytosol	IDA	J:75464
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:75464
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0050853	B cell receptor signaling pathway	IDA	J:121485
Biological Process	GO:0071216	cellular response to biotic stimulus	IDA	J:199058
Biological Process	GO:0071345	cellular response to cytokine stimulus	ISO	J:150450
Biological Process	GO:0071407	cellular response to organic cyclic compound	ISO	J:150450
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IBA	J:265628
Biological Process	GO:0071356	cellular response to tumor necrosis factor	IDA	J:211147
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	ISO	J:155856
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	ISO	J:164563
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	IBA	J:265628
Biological Process	GO:0042994	cytoplasmic sequestering of transcription factor	ISO	J:164563
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IDA	J:132126
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IDA	J:84896
Biological Process	GO:0010888	negative regulation of lipid storage	ISO	J:164563
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation	ISO	J:164563
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	IMP	J:97945
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	ISO	J:73065
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	IMP	J:97945
Biological Process	GO:0038061	NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:97945
Biological Process	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	IDA	J:132126
Biological Process	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	IDA	J:132126
Biological Process	GO:0010875	positive regulation of cholesterol efflux	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:138423
Biological Process	GO:0050729	positive regulation of inflammatory response	ISO	J:164563
Biological Process	GO:0051247	positive regulation of protein metabolic process	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	IMP	J:129237
Biological Process	GO:0006606	protein import into nucleus	IDA	J:75464
Biological Process	GO:0042127	regulation of cell population proliferation	IDA	J:75464
Biological Process	GO:0010468	regulation of gene expression	IMP	J:174553
Biological Process	GO:0043330	response to exogenous dsRNA	IDA	J:84896
Biological Process	GO:0032496	response to lipopolysaccharide	IDA	J:84896
Biological Process	GO:0032495	response to muramyl dipeptide	IDA	J:96035
Biological Process	GO:0035994	response to muscle stretch	IDA	J:163557
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	IDA	J:132126
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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