Dll1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Dll1
delta like canonical Notch ligand 1
MGI:104659

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005112	Notch binding	ISO	J:155856
Molecular Function	GO:0005112	Notch binding	IPI	J:180704
Molecular Function	GO:0005112	Notch binding	IPI	J:224738
Molecular Function	GO:0005112	Notch binding	ISO	J:164563
Molecular Function	GO:0005112	Notch binding	IPI	J:88030
Molecular Function	GO:0005112	Notch binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:88030
Molecular Function	GO:0005515	protein binding	IPI	J:245710
Molecular Function	GO:0005515	protein binding	IPI	J:173235
Molecular Function	GO:0005515	protein binding	IPI	J:227382
Molecular Function	GO:0005515	protein binding	IPI	J:225411
Molecular Function	GO:0005515	protein binding	IPI	J:180704
Molecular Function	GO:0005515	protein binding	IPI	J:208850
Molecular Function	GO:0005515	protein binding	IPI	J:117595
Molecular Function	GO:0005515	protein binding	IPI	J:114126
Molecular Function	GO:0005515	protein binding	IPI	J:84628
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Molecular Function	GO:0005515	protein binding	IPI	J:97329
Molecular Function	GO:0048018	receptor ligand activity	ISO	J:164563
Molecular Function	GO:0097110	scaffold protein binding	IPI	J:100814
Molecular Function	GO:0030957	Tat protein binding	ISO	J:164563
Cellular Component	GO:0005912	adherens junction	IDA	J:100814
Cellular Component	GO:0005912	adherens junction	IDA	J:208850
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:208850
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:101173
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0045121	membrane raft	IDA	J:224738
Cellular Component	GO:0045121	membrane raft	IDA	J:180704
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2060798
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2193065
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9012873
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9023350
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9793915
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:101173
Biological Process	GO:0009887	animal organ morphogenesis	NAS	J:56816
Biological Process	GO:0014002	astrocyte development	IMP	J:199717
Biological Process	GO:0009912	auditory receptor cell fate commitment	NAS	J:60836
Biological Process	GO:0009912	auditory receptor cell fate commitment	NAS	J:56415
Biological Process	GO:0007154	cell communication	IEA	J:72247
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007267	cell-cell signaling	IDA	J:131628
Biological Process	GO:0021688	cerebellar molecular layer formation	IMP	J:199717
Biological Process	GO:0021693	cerebellar Purkinje cell layer structural organization	IMP	J:199717
Biological Process	GO:0072583	clathrin-dependent endocytosis	ISO	J:155856
Biological Process	GO:0007386	compartment pattern specification	IMP	J:77247
Biological Process	GO:0007368	determination of left/right symmetry	IMP	J:83358
Biological Process	GO:0097102	endothelial tip cell fate specification	IMP	J:192694
Biological Process	GO:0097009	energy homeostasis	IMP	J:150183
Biological Process	GO:0001947	heart looping	IMP	J:83358
Biological Process	GO:0042386	hemocyte differentiation	IDA	J:131628
Biological Process	GO:0001701	in utero embryonic development	NAS	J:56816
Biological Process	GO:0002085	inhibition of neuroepithelial cell differentiation	IMP	J:107414
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	NAS	J:51632
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:107414
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	IMP	J:107414
Biological Process	GO:0048839	inner ear development	IMP	J:107414
Biological Process	GO:0048839	inner ear development	IMP	J:107414
Biological Process	GO:0048839	inner ear development	IMP	J:107414
Biological Process	GO:0042472	inner ear morphogenesis	NAS	J:51632
Biological Process	GO:0046331	lateral inhibition	IDA	J:143172
Biological Process	GO:0046331	lateral inhibition	IMP	J:177887
Biological Process	GO:0070986	left/right axis specification	IMP	J:83358
Biological Process	GO:0072070	loop of Henle development	IEP	J:97734
Biological Process	GO:0002315	marginal zone B cell differentiation	IMP	J:146621
Biological Process	GO:0002315	marginal zone B cell differentiation	IMP	J:90630
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0030099	myeloid cell differentiation	IDA	J:131628
Biological Process	GO:2000726	negative regulation of cardiac muscle cell differentiation	IMP	J:241479
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:220446
Biological Process	GO:0045596	negative regulation of cell differentiation	IMP	J:57072
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:135515
Biological Process	GO:0045605	negative regulation of epidermal cell differentiation	IMP	J:135515
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IMP	J:177887
Biological Process	GO:0034351	negative regulation of glial cell apoptotic process	IMP	J:199717
Biological Process	GO:0045611	negative regulation of hemocyte differentiation	IDA	J:131628
Biological Process	GO:0045608	negative regulation of inner ear auditory receptor cell differentiation	IMP	J:107414
Biological Process	GO:0032693	negative regulation of interleukin-10 production	ISO	J:164563
Biological Process	GO:0045638	negative regulation of myeloid cell differentiation	IDA	J:131628
Biological Process	GO:0045662	negative regulation of myoblast differentiation	IMP	J:119082
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:149456
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:156172
Biological Process	GO:0072006	nephron development	IMP	J:198632
Biological Process	GO:0007399	nervous system development	NAS	J:56816
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:107414
Biological Process	GO:0060563	neuroepithelial cell differentiation	IMP	J:107414
Biological Process	GO:0030182	neuron differentiation	IMP	J:156172
Biological Process	GO:0048665	neuron fate specification	IDA	J:143172
Biological Process	GO:0097150	neuronal stem cell population maintenance	IMP	J:224724
Biological Process	GO:0061314	Notch signaling involved in heart development	IC	J:83358
Biological Process	GO:0007219	Notch signaling pathway	IMP	J:149456
Biological Process	GO:0007219	Notch signaling pathway	TAS	J:97734
Biological Process	GO:0007219	Notch signaling pathway	IEP	J:199717
Biological Process	GO:0007219	Notch signaling pathway	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:0060853	Notch signaling pathway involved in arterial endothelial cell fate commitment	IMP	J:148902
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	NAS	J:51928
Biological Process	GO:0035265	organ growth	IMP	J:178999
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:178999
Biological Process	GO:0045807	positive regulation of endocytosis	IDA	J:224738
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:65682
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IMP	J:177887
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:224738
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IMP	J:149456
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:155856
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IMP	J:148902
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:224861
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:88030
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:97329
Biological Process	GO:0048633	positive regulation of skeletal muscle tissue growth	IMP	J:216287
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	IMP	J:192694
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:83358
Biological Process	GO:0072014	proximal tubule development	IEP	J:97734
Biological Process	GO:0009954	proximal/distal pattern formation	IMP	J:184814
Biological Process	GO:0008217	regulation of blood pressure	IMP	J:150183
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:188916
Biological Process	GO:0051302	regulation of cell division	IMP	J:177887
Biological Process	GO:0040008	regulation of growth	IMP	J:150183
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:143172
Biological Process	GO:0050767	regulation of neurogenesis	IMP	J:149456
Biological Process	GO:0048631	regulation of skeletal muscle tissue growth	IMP	J:119082
Biological Process	GO:0014807	regulation of somitogenesis	IMP	J:224861
Biological Process	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	IMP	J:148902
Biological Process	GO:0060041	retina development in camera-type eye	IMP	J:149456
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	IMP	J:149456
Biological Process	GO:0048630	skeletal muscle tissue growth	IMP	J:188916
Biological Process	GO:0098773	skin epidermis development	IMP	J:135515
Biological Process	GO:0001757	somite specification	IMP	J:88580
Biological Process	GO:0001756	somitogenesis	IMP	J:205623
Biological Process	GO:0001756	somitogenesis	IGI	J:98581
Biological Process	GO:0021510	spinal cord development	IMP	J:149456
Biological Process	GO:0003323	type B pancreatic cell development	IMP	J:184814

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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