Cdkn1b GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cdkn1b
cyclin dependent kinase inhibitor 1B
MGI:104565

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0030332	cyclin binding	ISO	J:164563
Molecular Function	GO:0030332	cyclin binding	IDA	J:211957
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IBA	J:265628
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IDA	J:19218
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	IDA	J:77997
Molecular Function	GO:0030544	Hsp70 protein binding	ISO	J:155856
Molecular Function	GO:0060090	molecular adaptor activity	ISO	J:164563
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:211957
Molecular Function	GO:0005515	protein binding	IPI	J:200302
Molecular Function	GO:0005515	protein binding	IPI	J:162977
Molecular Function	GO:0005515	protein binding	IPI	J:147145
Molecular Function	GO:0005515	protein binding	IPI	J:28743
Molecular Function	GO:0005515	protein binding	IPI	J:105045
Molecular Function	GO:0005515	protein binding	IPI	J:96084
Molecular Function	GO:0005515	protein binding	IPI	J:19218
Molecular Function	GO:0005515	protein binding	IPI	J:19218
Molecular Function	GO:0005515	protein binding	IPI	J:19218
Molecular Function	GO:0005515	protein binding	IPI	J:19218
Molecular Function	GO:0005515	protein binding	IPI	J:19218
Molecular Function	GO:0005515	protein binding	IPI	J:63241
Molecular Function	GO:0005515	protein binding	IPI	J:132869
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0004860	protein kinase inhibitor activity	ISO	J:164563
Molecular Function	GO:0019903	protein phosphatase binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:155856
Molecular Function	GO:0051087	protein-folding chaperone binding	IBA	J:265628
Molecular Function	GO:1990757	ubiquitin ligase activator activity	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:238763
Cellular Component	GO:0005737	cytoplasm	IDA	J:171468
Cellular Component	GO:0005737	cytoplasm	IDA	J:96084
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-5671980
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-9618292
Cellular Component	GO:0005829	cytosol	IDA	J:99181
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:238763
Cellular Component	GO:0005634	nucleus	IDA	J:218237
Cellular Component	GO:0005634	nucleus	IDA	J:157099
Cellular Component	GO:0005634	nucleus	IDA	J:102494
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:96084
Cellular Component	GO:0005634	nucleus	IDA	J:142037
Cellular Component	GO:0005634	nucleus	IDA	J:62413
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0006915	apoptotic process	IMP	J:115443
Biological Process	GO:0006915	apoptotic process	IMP	J:115443
Biological Process	GO:0048102	autophagic cell death	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0008219	cell death	ISO	J:155856
Biological Process	GO:0071236	cellular response to antibiotic	IDA	J:142037
Biological Process	GO:0071285	cellular response to lithium ion	ISO	J:142037
Biological Process	GO:0071407	cellular response to organic cyclic compound	IDA	J:142037
Biological Process	GO:1904019	epithelial cell apoptotic process	IMP	J:115443
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:115443
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:115443
Biological Process	GO:0060767	epithelial cell proliferation involved in prostate gland development	IMP	J:115443
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IDA	J:28743
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	IBA	J:265628
Biological Process	GO:0007507	heart development	IMP	J:211957
Biological Process	GO:0048839	inner ear development	IMP	J:53290
Biological Process	GO:0051179	localization	ISO	J:164563
Biological Process	GO:1905179	negative regulation of cardiac muscle tissue regeneration	IMP	J:211957
Biological Process	GO:1902807	negative regulation of cell cycle G1/S phase transition	ISO	J:164563
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0008285	negative regulation of cell population proliferation	ISO	J:155856
Biological Process	GO:0008285	negative regulation of cell population proliferation	IBA	J:265628
Biological Process	GO:0008285	negative regulation of cell population proliferation	IMP	J:73449
Biological Process	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	ISO	J:164563
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	IDA	J:77997
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	IMP	J:115443
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IMP	J:53290
Biological Process	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	IMP	J:115443
Biological Process	GO:0033673	negative regulation of kinase activity	ISO	J:164563
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	IBA	J:265628
Biological Process	GO:0042326	negative regulation of phosphorylation	ISO	J:164563
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0007219	Notch signaling pathway	IDA	J:218237
Biological Process	GO:0051168	nuclear export	ISO	J:164563
Biological Process	GO:0001890	placenta development	IGI	J:50769
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:84930
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:155856
Biological Process	GO:0031116	positive regulation of microtubule polymerization	IGI	J:96084
Biological Process	GO:0006813	potassium ion transport	IGI	J:116872
Biological Process	GO:0051726	regulation of cell cycle	ISO	J:164563
Biological Process	GO:0051726	regulation of cell cycle	IMP	J:211957
Biological Process	GO:1902806	regulation of cell cycle G1/S phase transition	ISO	J:164563
Biological Process	GO:0030334	regulation of cell migration	IDA	J:96084
Biological Process	GO:0042127	regulation of cell population proliferation	IEA	J:72247
Biological Process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0007096	regulation of exit from mitosis	IGI	J:50769
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:1902746	regulation of lens fiber cell differentiation	IGI	J:50769
Biological Process	GO:0007346	regulation of mitotic cell cycle	IDA	J:19218
Biological Process	GO:0007605	sensory perception of sound	IMP	J:53290

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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