GO Annotations Graph

• Symbol: Yap1
• Name: yes-associated protein 1
• ID: MGI:103262

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IDA	J:154728
Molecular Function	GO:0003682	chromatin binding	IDA	J:170963
Molecular Function	GO:0003682	chromatin binding	IDA	J:170963
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140678	molecular function inhibitor activity	ISO	J:164563
Molecular Function	GO:0070064	proline-rich region binding	IPI	J:140926
Molecular Function	GO:0070064	proline-rich region binding	IPI	J:140926
Molecular Function	GO:0005515	protein binding	IPI	J:213875
Molecular Function	GO:0005515	protein binding	IPI	J:235748
Molecular Function	GO:0005515	protein binding	IPI	J:182615
Molecular Function	GO:0005515	protein binding	IPI	J:245298
Molecular Function	GO:0005515	protein binding	IPI	J:118816
Molecular Function	GO:0005515	protein binding	IPI	J:257925
Molecular Function	GO:0005515	protein binding	IPI	J:171057
Molecular Function	GO:0005515	protein binding	IPI	J:211315
Molecular Function	GO:0005515	protein binding	IPI	J:200512
Molecular Function	GO:0005515	protein binding	IPI	J:169049
Molecular Function	GO:0005515	protein binding	IPI	J:170963
Molecular Function	GO:0005515	protein binding	IPI	J:129941
Molecular Function	GO:0005515	protein binding	IPI	J:182976
Molecular Function	GO:0005515	protein binding	IPI	J:154728
Molecular Function	GO:0005515	protein binding	IPI	J:154728
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:160813
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:118816
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:256712
Molecular Function	GO:0003713	transcription coactivator activity	IMP	J:256712
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0003714	transcription corepressor activity	IBA	J:265628
Molecular Function	GO:0008134	transcription factor binding	IPI	J:154728
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	IDA	J:256712
Cellular Component	GO:0005737	cytoplasm	IDA	J:147050
Cellular Component	GO:0005737	cytoplasm	IDA	J:213950
Cellular Component	GO:0005737	cytoplasm	IDA	J:190509
Cellular Component	GO:0005737	cytoplasm	IDA	J:218609
Cellular Component	GO:0005737	cytoplasm	IDA	J:213950
Cellular Component	GO:0005737	cytoplasm	IDA	J:160813
Cellular Component	GO:0005737	cytoplasm	IDA	J:134270
Cellular Component	GO:0005737	cytoplasm	IDA	J:201586
Cellular Component	GO:0005737	cytoplasm	IDA	J:199456
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:199301
Cellular Component	GO:0005829	cytosol	IDA	J:182976
Cellular Component	GO:0001674	female germ cell nucleus	IDA	J:256712
Cellular Component	GO:0016020	membrane	IDA	J:199301
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9796226
Cellular Component	GO:0005634	nucleus	IDA	J:219844
Cellular Component	GO:0005634	nucleus	IDA	J:169049
Cellular Component	GO:0005634	nucleus	IDA	J:238700
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:256712
Cellular Component	GO:0005634	nucleus	IDA	J:256712
Cellular Component	GO:0005634	nucleus	IDA	J:213950
Cellular Component	GO:0005634	nucleus	IDA	J:199301
Cellular Component	GO:0005634	nucleus	IDA	J:142508
Cellular Component	GO:0005634	nucleus	IDA	J:147050
Cellular Component	GO:0005634	nucleus	IDA	J:134270
Cellular Component	GO:0005634	nucleus	IDA	J:147050
Cellular Component	GO:0005634	nucleus	IDA	J:160813
Cellular Component	GO:0005634	nucleus	IDA	J:201586
Cellular Component	GO:0005634	nucleus	IDA	J:154728
Cellular Component	GO:0005634	nucleus	IDA	J:184811
Cellular Component	GO:0005634	nucleus	IDA	J:182976
Cellular Component	GO:0005634	nucleus	IDA	J:190509
Cellular Component	GO:0005634	nucleus	IDA	J:213950
Cellular Component	GO:0140552	TEAD-YAP complex	ISO	J:164563
Cellular Component	GO:0140552	TEAD-YAP complex	IPI	J:314641
Cellular Component	GO:0005667	transcription regulator complex	IGI	J:102951
Cellular Component	GO:0005667	transcription regulator complex	IGI	J:102951
Cellular Component	GO:0005667	transcription regulator complex	IGI	J:102951
Cellular Component	GO:0005667	transcription regulator complex	IGI	J:102951
Biological Process	GO:0001824	blastocyst development	IMP	J:256712
Biological Process	GO:0001824	blastocyst development	IMP	J:256712
Biological Process	GO:0060449	bud elongation involved in lung branching	IMP	J:213950
Biological Process	GO:0060070	canonical Wnt signaling pathway	IDA	J:141457
Biological Process	GO:0061026	cardiac muscle tissue regeneration	IMP	J:200670
Biological Process	GO:0000902	cell morphogenesis	IMP	J:160813
Biological Process	GO:0008283	cell population proliferation	ISO	J:164563
Biological Process	GO:0008283	cell population proliferation	IDA	J:141457
Biological Process	GO:0008283	cell population proliferation	IMP	J:154782
Biological Process	GO:0008283	cell population proliferation	IDA	J:154728
Biological Process	GO:0008283	cell population proliferation	IDA	J:141457
Biological Process	GO:0071480	cellular response to gamma radiation	ISO	J:164563
Biological Process	GO:0071300	cellular response to retinoic acid	IDA	J:182976
Biological Process	GO:0060242	contact inhibition	ISO	J:164563
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IGI	J:131426
Biological Process	GO:0003143	embryonic heart tube morphogenesis	IGI	J:131426
Biological Process	GO:1903703	enterocyte differentiation	IDA	J:141457
Biological Process	GO:0050673	epithelial cell proliferation	IDA	J:141457
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IGI	J:141457
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	IGI	J:141457
Biological Process	GO:0002067	glandular epithelial cell differentiation	IDA	J:141457
Biological Process	GO:0002067	glandular epithelial cell differentiation	IDA	J:141457
Biological Process	GO:0003015	heart process	IMP	J:200670
Biological Process	GO:0035329	hippo signaling	NAS	J:320613
Biological Process	GO:0035329	hippo signaling	IBA	J:265628
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0035329	hippo signaling	IGI	J:134270
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	IDA	J:219844
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0060576	intestinal epithelial cell development	ISO	J:164563
Biological Process	GO:0060576	intestinal epithelial cell development	IDA	J:219844
Biological Process	GO:0060575	intestinal epithelial cell differentiation	IDA	J:141457
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IMP	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0030216	keratinocyte differentiation	IGI	J:134270
Biological Process	GO:0048368	lateral mesoderm development	IGI	J:131426
Biological Process	GO:0048368	lateral mesoderm development	IGI	J:131426
Biological Process	GO:0060487	lung epithelial cell differentiation	IMP	J:213950
Biological Process	GO:1902018	negative regulation of cilium assembly	ISO	J:164563
Biological Process	GO:1904036	negative regulation of epithelial cell apoptotic process	ISO	J:164563
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IDA	J:141457
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IDA	J:141457
Biological Process	GO:0030857	negative regulation of epithelial cell differentiation	IDA	J:141457
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	IGI	J:141457
Biological Process	GO:0045599	negative regulation of fat cell differentiation	ISO	J:164563
Biological Process	GO:0010629	negative regulation of gene expression	ISO	J:164563
Biological Process	GO:2000737	negative regulation of stem cell differentiation	IDA	J:160813
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0030903	notochord development	IGI	J:131426
Biological Process	GO:0030903	notochord development	IGI	J:131426
Biological Process	GO:0035265	organ growth	IDA	J:141457
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:131426
Biological Process	GO:0048339	paraxial mesoderm development	IGI	J:131426
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IDA	J:141457
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	IDA	J:200670
Biological Process	GO:0030307	positive regulation of cell growth	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:154782
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:141457
Biological Process	GO:0008284	positive regulation of cell population proliferation	IDA	J:154728
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IMP	J:256712
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	IDA	J:141457
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	ISO	J:164563
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:219844
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ISO	J:164563
Biological Process	GO:0046622	positive regulation of organ growth	IDA	J:141457
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	IMP	J:169049
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	IMP	J:160813
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:314641
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:160813
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:102951
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:182976
Biological Process	GO:0050847	progesterone receptor signaling pathway	ISO	J:164563
Biological Process	GO:0065003	protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	IGI	J:201586
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:142508
Biological Process	GO:0010468	regulation of gene expression	IGI	J:237140
Biological Process	GO:0010468	regulation of gene expression	IGI	J:237140
Biological Process	GO:0010837	regulation of keratinocyte proliferation	IMP	J:134270
Biological Process	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	IGI	J:201586
Biological Process	GO:0050767	regulation of neurogenesis	ISO	J:218609
Biological Process	GO:0072091	regulation of stem cell proliferation	ISO	J:218609
Biological Process	GO:0072091	regulation of stem cell proliferation	IMP	J:154782
Biological Process	GO:0072091	regulation of stem cell proliferation	IGI	J:218609
Biological Process	GO:0072091	regulation of stem cell proliferation	IDA	J:154728
Biological Process	GO:0032570	response to progesterone	ISO	J:164563
Biological Process	GO:0035019	somatic stem cell population maintenance	IDA	J:141457
Biological Process	GO:0001894	tissue homeostasis	IMP	J:200670
Biological Process	GO:0001829	trophectodermal cell differentiation	IMP	J:256712
Biological Process	GO:0001570	vasculogenesis	IMP	J:102253
Biological Process	GO:0042060	wound healing	IMP	J:200670