H2-Ab1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

H2-Ab1
histocompatibility 2, class II antigen A, beta 1
MGI:103070

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0023026	MHC class II protein complex binding	IBA	J:265628
Molecular Function	GO:0042605	peptide antigen binding	IDA	J:88532
Molecular Function	GO:0042605	peptide antigen binding	IDA	J:65235
Molecular Function	GO:1990405	protein antigen binding	IPI	J:169822
Molecular Function	GO:0005515	protein binding	IPI	J:88528
Molecular Function	GO:0005515	protein binding	IPI	J:88528
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0015643	toxic substance binding	IPI	J:169822
Molecular Function	GO:0031625	ubiquitin protein ligase binding	IPI	J:134430
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005769	early endosome	IDA	J:88531
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:4119
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31786
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:88532
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31625
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:85084
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:31624
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87421
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:68798
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:87420
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:4119
Cellular Component	GO:0005622	intracellular anatomical structure	IDA	J:88529
Cellular Component	GO:0016020	membrane	IDA	J:88530
Cellular Component	GO:0042613	MHC class II protein complex	IBA	J:265628
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:88532
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:31786
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:31624
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:85084
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:68798
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:31625
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:4119
Cellular Component	GO:0042613	MHC class II protein complex	IDA	J:88528
Cellular Component	GO:0005771	multivesicular body	IDA	J:88531
Cellular Component	GO:0005886	plasma membrane	IDA	J:4119
Cellular Component	GO:0005886	plasma membrane	IDA	J:88529
Cellular Component	GO:0005886	plasma membrane	IDA	J:31786
Cellular Component	GO:0005886	plasma membrane	IDA	J:88531
Cellular Component	GO:0005886	plasma membrane	IDA	J:88528
Biological Process	GO:0002250	adaptive immune response	IEA	J:60000
Biological Process	GO:0019882	antigen processing and presentation	IDA	J:88532
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IBA	J:265628
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:88532
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:72827
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:31624
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:65235
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:4119
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:88533
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:31625
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	IDA	J:85084
Biological Process	GO:0048002	antigen processing and presentation of peptide antigen	IDA	J:65235
Biological Process	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	IEA	J:60000
Biological Process	GO:0002344	B cell affinity maturation	IDA	J:169911
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:169816
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:169823
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:169824
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:169912
Biological Process	GO:0071346	cellular response to type II interferon	IDA	J:169821
Biological Process	GO:0006955	immune response	IMP	J:65736
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	IBA	J:265628
Biological Process	GO:0002503	peptide antigen assembly with MHC class II protein complex	IBA	J:265628
Biological Process	GO:0046635	positive regulation of alpha-beta T cell activation	IMP	J:169994
Biological Process	GO:0046635	positive regulation of alpha-beta T cell activation	IDA	J:169793
Biological Process	GO:0046635	positive regulation of alpha-beta T cell activation	TAS	J:20420
Biological Process	GO:0002579	positive regulation of antigen processing and presentation	IDA	J:169793
Biological Process	GO:0050870	positive regulation of T cell activation	IBA	J:265628
Biological Process	GO:0002827	positive regulation of T-helper 1 type immune response	IDA	J:169793

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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