GO Annotations Graph

• Symbol: Pou2f2
• Name: POU domain, class 2, transcription factor 2
• ID: MGI:101897

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:88240
Molecular Function	GO:0003677	DNA binding	IDA	J:88916
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:88916
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:190912
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:155856
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:88240
Molecular Function	GO:0003700	DNA-binding transcription factor activity	IDA	J:88916
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:24361
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:88916
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:24361
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:119653
Molecular Function	GO:0043565	sequence-specific DNA binding	IDA	J:164346
Molecular Function	GO:0043565	sequence-specific DNA binding	ISO	J:73065
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0015606	spermidine transmembrane transporter activity	IDA	J:331353
Molecular Function	GO:0000976	transcription cis-regulatory region binding	IDA	J:190912
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:73065
Cellular Component	GO:0005634	nucleus	IDA	J:88240
Cellular Component	GO:0005634	nucleus	IDA	J:88916
Biological Process	GO:0048469	cell maturation	IMP	J:88240
Biological Process	GO:0098586	cellular response to virus	IMP	J:190912
Biological Process	GO:0002377	immunoglobulin production	IMP	J:88240
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	IMP	J:4555
Biological Process	GO:0002335	mature B cell differentiation	IMP	J:4555
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:88916
Biological Process	GO:0032755	positive regulation of interleukin-6 production	IDA	J:190912
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:88916
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:190912
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:88240
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0015848	spermidine transport	IDA	J:331353