GO Annotations Graph

• Symbol: Ppard
• Name: peroxisome proliferator activator receptor delta
• ID: MGI:101884

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IDA	J:19422
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:228110
Molecular Function	GO:0008047	enzyme activator activity	TAS	J:116961
Molecular Function	GO:0005504	fatty acid binding	ISO	J:155856
Molecular Function	GO:0070539	linoleic acid binding	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:155856
Molecular Function	GO:0004879	nuclear receptor activity	ISO	J:164563
Molecular Function	GO:0004879	nuclear receptor activity	IBA	J:265628
Molecular Function	GO:0004879	nuclear receptor activity	TAS	J:63040
Molecular Function	GO:0016501	prostacyclin receptor activity	TAS	J:113889
Molecular Function	GO:0005515	protein binding	IPI	J:244975
Molecular Function	GO:0005515	protein binding	IPI	J:255965
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:56144
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0005515	protein binding	IPI	J:114147
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:0043565	sequence-specific DNA binding	IEA	J:72247
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0000785	chromatin	IDA	J:228110
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IDA	J:56144
Biological Process	GO:0060612	adipose tissue development	IMP	J:73557
Biological Process	GO:0042640	anagen	IMP	J:96826
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0008366	axon ensheathment	IMP	J:63040
Biological Process	GO:0030154	cell differentiation	IBA	J:265628
Biological Process	GO:0030154	cell differentiation	IDA	J:107381
Biological Process	GO:0030154	cell differentiation	IMP	J:107381
Biological Process	GO:0008283	cell population proliferation	IMP	J:73557
Biological Process	GO:0008283	cell population proliferation	IMP	J:73557
Biological Process	GO:0031589	cell-substrate adhesion	IMP	J:71272
Biological Process	GO:0071456	cellular response to hypoxia	IGI	J:203819
Biological Process	GO:0071456	cellular response to hypoxia	IGI	J:203819
Biological Process	GO:0071456	cellular response to hypoxia	IGI	J:203819
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:155856
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:164563
Biological Process	GO:0007566	embryo implantation	TAS	J:113889
Biological Process	GO:0007566	embryo implantation	TAS	J:114147
Biological Process	GO:0007566	embryo implantation	IDA	J:56144
Biological Process	GO:0097009	energy homeostasis	IMP	J:147973
Biological Process	GO:0097009	energy homeostasis	ISO	J:164563
Biological Process	GO:0008544	epidermis development	TAS	J:63040
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:73557
Biological Process	GO:0050673	epithelial cell proliferation	IGI	J:88127
Biological Process	GO:0070341	fat cell proliferation	IMP	J:73557
Biological Process	GO:0006635	fatty acid beta-oxidation	IEP	J:114135
Biological Process	GO:0019395	fatty acid oxidation	ISO	J:155856
Biological Process	GO:0015908	fatty acid transport	IEP	J:114135
Biological Process	GO:0009755	hormone-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0051546	keratinocyte migration	IMP	J:71272
Biological Process	GO:0043616	keratinocyte proliferation	IMP	J:71271
Biological Process	GO:0006629	lipid metabolic process	ISO	J:155856
Biological Process	GO:0006629	lipid metabolic process	IMP	J:63040
Biological Process	GO:0006629	lipid metabolic process	IMP	J:107381
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:155856
Biological Process	GO:0030308	negative regulation of cell growth	ISO	J:155856
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	ISO	J:155856
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	IGI	J:88127
Biological Process	GO:0050728	negative regulation of inflammatory response	ISO	J:155856
Biological Process	GO:0050728	negative regulation of inflammatory response	IBA	J:265628
Biological Process	GO:1902894	negative regulation of miRNA transcription	IDA	J:228110
Biological Process	GO:0045662	negative regulation of myoblast differentiation	IMP	J:183730
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	ISO	J:155856
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:19422
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	IDA	J:107381
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	IDA	J:107381
Biological Process	GO:0008654	phospholipid biosynthetic process	ISO	J:155856
Biological Process	GO:0001890	placenta development	IMP	J:73557
Biological Process	GO:0001890	placenta development	IMP	J:73557
Biological Process	GO:0001890	placenta development	IMP	J:73557
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045684	positive regulation of epidermis development	ISO	J:155856
Biological Process	GO:0070346	positive regulation of fat cell proliferation	IMP	J:73557
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	IMP	J:183730
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO	J:155856
Biological Process	GO:2000288	positive regulation of myoblast proliferation	IMP	J:183730
Biological Process	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity	IMP	J:147973
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	IDA	J:107381
Biological Process	GO:0043415	positive regulation of skeletal muscle tissue regeneration	IMP	J:183730
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0006029	proteoglycan metabolic process	ISO	J:155856
Biological Process	GO:0042127	regulation of cell population proliferation	IGI	J:93551
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0050678	regulation of epithelial cell proliferation	IMP	J:63040
Biological Process	GO:0045598	regulation of fat cell differentiation	IMP	J:73557
Biological Process	GO:0045598	regulation of fat cell differentiation	IMP	J:73557
Biological Process	GO:0050796	regulation of insulin secretion	NAS	J:114135
Biological Process	GO:0019216	regulation of lipid metabolic process	IBA	J:265628
Biological Process	GO:0014842	regulation of skeletal muscle satellite cell proliferation	IMP	J:183730
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0042311	vasodilation	ISO	J:155856
Biological Process	GO:0006776	vitamin A metabolic process	ISO	J:155856
Biological Process	GO:0042060	wound healing	IMP	J:71272