GO Annotations Graph

• Symbol: Scnn1a
• Name: sodium channel, nonvoltage-gated 1 alpha
• ID: MGI:101782

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	ISO	J:155856
Molecular Function	GO:0015280	ligand-gated sodium channel activity	ISO	J:155856
Molecular Function	GO:0015280	ligand-gated sodium channel activity	ISO	J:155856
Molecular Function	GO:0015280	ligand-gated sodium channel activity	ISO	J:164563
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IBA	J:265628
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IGI	J:126754
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IGI	J:126754
Molecular Function	GO:0015280	ligand-gated sodium channel activity	IDA	J:56566
Molecular Function	GO:0005272	sodium channel activity	IDA	J:136460
Molecular Function	GO:0015081	sodium ion transmembrane transporter activity	ISO	J:297461
Molecular Function	GO:0050699	WW domain binding	ISO	J:155856
Molecular Function	GO:0050699	WW domain binding	ISO	J:164563
Molecular Function	GO:0050699	WW domain binding	IPI	J:54531
Molecular Function	GO:0050699	WW domain binding	IPI	J:54531
Cellular Component	GO:0001669	acrosomal vesicle	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:164563
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0060170	ciliary membrane	ISO	J:164563
Cellular Component	GO:0005929	cilium	IEA	J:60000
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005829	cytosol	IDA	J:172256
Cellular Component	GO:0009897	external side of plasma membrane	IDA	J:126754
Cellular Component	GO:0070062	extracellular exosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:172256
Cellular Component	GO:0016020	membrane	IDA	J:126754
Cellular Component	GO:0016020	membrane	IDA	J:56566
Cellular Component	GO:0031514	motile cilium	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0034706	sodium channel complex	ISO	J:164563
Cellular Component	GO:0034706	sodium channel complex	IDA	J:297464
Cellular Component	GO:0034706	sodium channel complex	IDA	J:286836
Cellular Component	GO:0034706	sodium channel complex	IGI	J:126754
Cellular Component	GO:0034706	sodium channel complex	IGI	J:126754
Cellular Component	GO:0097228	sperm principal piece	ISO	J:155856
Biological Process	GO:0071468	cellular response to acidic pH	ISO	J:164563
Biological Process	GO:1904045	cellular response to aldosterone	NAS	J:320166
Biological Process	GO:1904045	cellular response to aldosterone	IDA	J:160934
Biological Process	GO:1904117	cellular response to vasopressin	NAS	J:320166
Biological Process	GO:0006883	intracellular sodium ion homeostasis	IDA	J:91291
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:155856
Biological Process	GO:0006883	intracellular sodium ion homeostasis	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	ISO	J:164563
Biological Process	GO:0008217	regulation of blood pressure	NAS	J:320166
Biological Process	GO:0050878	regulation of body fluid levels	ISO	J:155856
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0050914	sensory perception of salty taste	NAS	J:320167
Biological Process	GO:0050915	sensory perception of sour taste	NAS	J:320167
Biological Process	GO:0050909	sensory perception of taste	IEA	J:60000
Biological Process	GO:0055078	sodium ion homeostasis	ISO	J:164563
Biological Process	GO:0098719	sodium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:0098719	sodium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:0098719	sodium ion import across plasma membrane	IDA	J:91291
Biological Process	GO:0035725	sodium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0035725	sodium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006814	sodium ion transport	ISO	J:155856
Biological Process	GO:0006814	sodium ion transport	IGI	J:126754
Biological Process	GO:0006814	sodium ion transport	IGI	J:136460
Biological Process	GO:0006814	sodium ion transport	IGI	J:136460
Biological Process	GO:0006814	sodium ion transport	IDA	J:56566
Biological Process	GO:0006814	sodium ion transport	IGI	J:126754