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War Gene Detail
Summary
  • Symbol
    War
  • Name
    warfarin resistance
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98944
    NCBI Gene: 109735
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 7, Syntenic
  • Mapping Data
    8 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from multigenic genotypes
    7 phenotype references
  • All Mutations and Alleles
    1
  • Chemically induced (other)
    1
Heterozygotes for an allele found in a wild population exhibit greater resistance to a diet containing the anti-coagulant warfarin, with greater penetrance in females than in males.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Sequences &
Gene Models
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Other
Accession IDs
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MGD-MRK-15428
References
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  • Summaries
    All 11
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:220223 ROWE FP, et al., THE TOXICITY OF 0-025 PER CENT WARFARIN TO WILD HOUSE-MICE (MUS MUSCULUS L.). J Hyg (Lond). 1964 Sep;62:389-93
  • Latest
    J:101681 Pelz HJ, et al., The genetic basis of resistance to anticoagulants in rodents. Genetics. 2005 Aug;170(4):1839-47

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory