Tcm
Gene Detail

Symbol Name ID

Tcm total cataract with microphthalmia MGI:98533

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 4
Syntenic

Mapping data(2)

Alleles and phenotypes

All alleles(1) : Radiation induced(1)
 

Both homozygotes and heterozygotes exhibit total opacity and dysplasia of the lens, reduced pupils, iris dysplasia, and microphthalmia.

 
Human Diseases Modeled Using Mouse Tcm (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(2)

Other database links

Entrez Gene

110289

References

(Earliest) J:52633 Graw J, et al., Dominant cataract and recessive specific locus mutations in offspring of X-irradiated male mice. Mutat Res. 1986 Jan-Feb;159(1-2):47-54
(Latest) J:100636 Wang KS, et al., Genetic and phenotypic analysis of Tcm, a mutation affecting early eye development. Mamm Genome. 2005 May;16(5):332-43
All references(5)

Other accession IDs

MGD-MRK-14806