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Tcm
Gene Detail
Symbol

Name
ID
Tcm
total cataract with microphthalmia
MGI:98533
Feature Type
heritable phenotypic marker
Genetic Map
Chromosome 4
Syntenic

Mapping data(2)
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Radiation induced(1)
 
Both homozygotes and heterozygotes exhibit total opacity and dysplasia of the lens, reduced pupils, iris dysplasia, and microphthalmia.
 
Phenotype Images(2)
Other database
links
Entrez Gene110289
References
(Earliest) J:52633 Graw J, et al., Dominant cataract and recessive specific locus mutations in offspring of X-irradiated male mice. Mutat Res. 1986 Jan-Feb;159(1-2):47-54
(Latest) J:100636 Wang KS, et al., Genetic and phenotypic analysis of Tcm, a mutation affecting early eye development. Mamm Genome. 2005 May;16(5):332-43
All references(5)
Other
accession IDs
MGD-MRK-14806

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory