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Tcm Gene Detail
Summary
  • Symbol
    Tcm
  • Name
    total cataract with microphthalmia
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98533
    NCBI Gene: 110289
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 4, Syntenic
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotypes from 1 allele in 2 genetic backgrounds
    2 images
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Radiation induced
    1
Both homozygotes and heterozygotes exhibit total opacity and dysplasia of the lens, reduced pupils, iris dysplasia, and microphthalmia.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-14806
References
more
  • Summaries
    All 5
    Phenotypes 4
  • Earliest
    J:52633 Graw J, et al., Dominant cataract and recessive specific locus mutations in offspring of X-irradiated male mice. Mutat Res. 1986 Jan-Feb;159(1-2):47-54
  • Latest
    J:100636 Wang KS, et al., Genetic and phenotypic analysis of Tcm, a mutation affecting early eye development. Mamm Genome. 2005 May;16(5):332-43

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory