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Ren2 Gene Detail
Summary
  • Symbol
    Ren2
  • Name
    renin 2 tandem duplication of Ren1
  • Synonyms
    Ren, Ren-2, Ren-B, Rn-2, Rnr
Location & Maps
more
  • Sequence Map
    Genome coordinates not available
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    43 experiments
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
  • All Mutations and Alleles
    1
  • Targeted
    1
  • Incidental Mutations
Mice homozygous for a targeted null mutation are viable and fertile; no defects in the function of the renin-angiotensin system were detected and blood pressure regulation was normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic K02597 GenBank | EMBL | DDBJ | MGI Sequence Detail 640 Not Specified ±  kb
transcript NM_031193 RefSeq | MGI Sequence Detail 1547 FVB/N  
polypeptide P00796 UniProt | EBI | MGI Sequence Detail 401 Not Applicable  
For the selected sequence
Polymorphisms
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Protein
Information
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Molecular
Reagents
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  • All nucleic 27
    Genomic 10
    cDNA 15
    Primer pair 1
    Other 1
Other
Accession IDs
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MGD-MRK-13833, MGD-MRK-13834, MGD-MRK-13835, MGD-MRK-13837, MGD-MRK-13839, MGD-MRK-13918, MGD-MRK-13951
References
more
  • Summaries
    All 80
    Developmental Gene Expression 12
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:5794 Wilson CM, et al., Genetic control of renin activity in the submaxillary gland of the mouse. Proc Natl Acad Sci U S A. 1977 Mar;74(3):1185-9
  • Latest
    J:227300 Lin EE, et al., Aldo-keto reductase 1b7, a novel marker for renin cells, is regulated by cyclic AMP signaling. Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R576-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory