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Qdpr
Gene Detail
 Symbol
Name
ID
Qdpr
quinoid dihydropteridine reductase
MGI:97836
Synonyms 2610008L04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 5
24.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(21)
Sequence Map
Chr5:45434032-45450235 bp, - strand
From VEGA annotation of GRCm38

  16204 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:271  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: dihydropteridine reductase
Gene Tree: Qdpr

Human
homologs
Human Homolog QDPR, quinoid dihydropteridine reductase
NCBI Gene ID 5860
neXtProt AC  NX_P09417
Human Synonyms  DHPR, PKU2, SDR33C1
Human Chr (Location)  4p15.31; chr4:17486393-17512234 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human QDPR
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Chemically induced (ENU)(1) Gene trapped(1) Radiation induced(1) Targeted(4)
Genomic Mutations involving Qdpr (2)
Incidental mutations (data from Mutagenetix )
 
A portion of mice homozygous for a knock-out allele display abnormal rib-sternum attachment, a split xiphoid process, and lumbar vertebral transformation.
 
Alleles Annotated to Human Diseases(2)   
Interactions
Qdpr interacts with 76 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process metabolic process, oxidation-reduction process, ...
Component cytoplasm, cytosol, ...
Function 6,7-dihydropteridine reductase activity, NADH binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (111)    Tissues (96)    Images (21)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 111
cDNA source data(137)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(141) cDNA(138) Primer pair(2) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027775 (Evidence)
Ensembl Gene ModelENSMUSG00000015806 (Evidence)
Entrez Gene110391 (Evidence)
UniGene30204
DFCITC1572062
DoTSDT.535975, DT.94203582
NIA Mouse Gene IndexU026168
EC1.5.1.34
Consensus CDS ProjectCCDS19272.1
International Mouse Knockout Project StatusQdpr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027775 VEGA Gene Model | MGI Sequence Detail 16204 C57BL/6J ±  kb
transcript OTTMUST00000068743 VEGA | MGI Sequence Detail 1400 Not Applicable 
polypeptide OTTMUSP00000034817 VEGA | MGI Sequence Detail 241 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(2) UniProt(4)
Polymorphisms RFLP(9) : SNPs within 2kb(138 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR020904 Short-chain dehydrogenase/reductase, conserved site
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
Protein Ontology PR:000013562 dihydropteridine reductase
References (Earliest) J:8865 MacDonald ME, et al., Physical and genetic localization of quinonoid dihydropteridine reductase gene (QDPR) on short arm of chromosome 4. Somat Cell Mol Genet. 1987 Sep;13(5):569-74
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(57)
Other
accession IDs
MGD-MRK-13735, MGI:1196320, MGI:1917283

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory