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Pepb Gene Detail
Summary
  • Symbol
    Pepb
  • Name
    peptidase B
  • Synonyms
    Pep2, Pep-2, Trip-1
  • Feature Type
    unclassified gene
  • IDs
    MGI:97540
    NCBI Gene: 109628
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 10, Syntenic
  • Mapping Data
    9 experiments
Homology
more
  • Human Ortholog
    PEPB, peptidase B
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PEPB, peptidase B
  • Links
    NCBI Gene ID: 5182

  • Chr Location
    12q21
Mutations,
Alleles, and
Phenotypes
less
This locus is the structural locus for a tripeptidase (PEPB). Two ENU-induced mutations have been identified, one of which determines an electrophoretic variant migrating less anodal than the common allele.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-13232, MGD-MRK-13237, MGD-MRK-15228
References
more
  • Summaries
    All 20
    Gene Ontology 3
  • Earliest
    J:5133 Lewis WH, et al., Electrophoretic heterogeneity of mouse erythrocyte peptidases. Biochem Genet. 1969 Oct;3(5):493-8
  • Latest
    J:196769 Ramachandran A, et al., Localization of transforming growth factor beta receptor II interacting protein-1 in bone and teeth: implications in matrix mineralization. J Histochem Cytochem. 2012 Apr;60(4):323-37
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory